Cognitive Behavioral Therapy for Arthritis Pain and Insomnia in Older Adults

认知行为疗法治疗老年人关节炎疼痛和失眠

• 批准号: 7984197
• 负责人: SUSAN M MCCURRY
• 金额: $ 10.37万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-09-01 至 2013-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7984197
• 关键词: Acute; Address; Administrative Supplement; Adult; Affect; Aftercare; Age; American; Arthritis; Attention; Behavior Therapy; Behavioral; Clinical; Cognition; Cognitive; Cognitive Therapy; Cost Savings; Data; Data Analyses; Degenerative polyarthritis; Disease Management; Effectiveness; Elderly; Enrollment; Extramural Activities; Functional disorder; Funding; Grant; Health; Health Care Costs; Human Resources; Intervention; Intervention Studies; Interview; Link; Literature; Measurement; Older Population; Outcome Measure; Pain; Pain management; Parents; Participant; Patients; Peer Review; Persons; Principal Investigator; Protocols documentation; Randomized; Randomized Controlled Trials; Relative (related person); Reporting; Sampling; Sampling Studies; Short-Term Memory; Sleep; Sleep disturbances; Sleeplessness; Symptoms; Testing; Time; chronic pain; cognitive function; cost; economic implication; executive function; experience; follow-up; functional outcomes; health care service utilization; improved; indexing; intervention effect; novel; parent grant; parent project; primary outcome; programs; response

DESCRIPTION (provided by applicant): This is a competing revision (supplement) application for 1 R01 AG031126, Cognitive Behavioral Therapy for Arthritis Pain and Insomnia in Older Adults, M. V. Vitiello Contact Principal Investigator. The aim of the funded randomized controlled trial parent study is to assess whether a behavioral intervention that targets both pain and sleep disturbance vs. one that targets pain alone vs. an attention-control, will substantially improve pain- and sleep-related symptoms, functional outcome, and health care utilization in a large sample of older adults with co-morbid osteoarthritis and insomnia. Parent study assessments are made pretreatment, post-treatment and at 9 and 18 month follow-ups. Numerous reports in the literature link pain and sleep disturbance to compromised cognitive function; an effect that is particularly exacerbated for older adults when these conditions co-occur. Therefore, an intervention which is likely to reduce pain and improve sleep will likely have a desirable cognition-enhancing effect as well, particularly for cognitive abilities most susceptible to the influences of these conditions. Funds are requested to support the addition of a cognitive assessment to the 9 and 18 month follow-up assessments of the parent study and the analysis of the cognitive data. This will allow us to examine the potential acute and long term cognitive benefits associated with two behavioral interventions vs. a control in older adults with co-morbid osteoarthritis and insomnia. PUBLIC HEALTH RELEVANCE: Osteoarthritis (OA) pain debilitates half of all older adults, most of whom also experience significant sleep disturbance. The parent project seeks to determine whether a cognitive-behavioral treatment targeting both pain and co-morbid sleep disturbance in older adults with painful OA results in substantially greater reductions in pain and improvements in sleep and functional outcomes compared a cognitive-behavioral treatment targeting pain alone, or an attention-control condition. This competing revision(supplement) seeks to add a cognitive assessment to the outcome measures of the parent study since an intervention which is likely to reduce pain and improve sleep will likely have a desirable cognition-enhancing effect as well. Given the recent limitations on pharmacologic options for effective management of OA pain, this project has major implications for improving management of both pain and co-morbid sleep disturbance in the rapidly growing population of older Americans suffering from OA.

描述（由申请人提供）：这是1 R 01 AG 031126，老年人关节炎疼痛和关节炎的认知行为治疗，M。V. Vitiello联系主要研究者。资助的随机对照试验母研究的目的是评估针对疼痛和睡眠障碍的行为干预与仅针对疼痛的行为干预相比，注意力控制，是否会显著改善疼痛和睡眠相关症状，功能结局，以及在患有骨关节炎和失眠症的老年人大样本中的医疗保健利用。在治疗前、治疗后以及9个月和18个月随访时进行母研究评估。文献中的许多报告将疼痛和睡眠障碍与认知功能受损联系起来;当这些情况同时发生时，老年人的影响尤其严重。因此，可能减轻疼痛和改善睡眠的干预措施也可能具有理想的认知增强效果，特别是对于认知能力。 易受这些条件的影响。要求提供资金，以支持在母研究的9个月和18个月随访评估中增加认知评估以及认知数据分析。这将使我们能够检查与两种行为干预相关联的潜在急性和长期认知益处。在患有共病骨关节炎和失眠的老年人中进行对照。 公共卫生相关性：骨关节炎（OA）疼痛使一半的老年人衰弱，其中大多数人还经历了严重的睡眠障碍。该母项目旨在确定与仅针对疼痛或注意力控制条件的认知行为治疗相比，针对疼痛和合并症睡眠障碍的认知行为治疗是否会显著减少疼痛并改善睡眠和功能结局。这一竞争性修订（补充）旨在将认知评估添加到母研究的结局指标中，因为可能减轻疼痛和改善睡眠的干预措施也可能具有理想的认知增强效果。鉴于最近有效治疗OA疼痛的药物选择的局限性，该项目具有重大意义 用于改善快速增长的患有OA的美国老年人中的疼痛和共病睡眠障碍的管理。