SOUTHWEST ONCOLOGY GROUP STATISTICAL CENTER

西南肿瘤集团统计中心

• 批准号: 8213593
• 负责人: Michael L. LeBlanc
• 金额: $ 460.67万
• 依托单位: FRED HUTCHINSON CANCER RESEARCH CENTER
• 依托单位国家: 美国
• 财政年份: 1985
• 资助国家: 美国
• 起止时间: 1985-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8213593
• 关键词: Address; Adult; Cancer Control Research; Cancer Survivor; Caring; Clinical Research Associate; Clinical Trials; Collaborations; Collection; Computer software; Conduct Clinical Trials; Data; Data Analyses; Data Collection; Data Storage and Retrieval; Development; Electronics; Eligibility Determination; Ensure; Evaluation; Experimental Designs; Future; Goals; Guidelines; Institution; Maintenance; Malignant Neoplasms; Methods; Mission; Monitor; Nurses; Oncologist; Online Systems; Patients; Performance; Phase; Probability; Procedures; Process; Protocols documentation; Publications; Quality Control; Quality of life; Randomized; Research; Research Design; Research Personnel; Research Support; Resources; Role; Sample Size; Scientific Advances and Accomplishments; Southwest Oncology Group; Survival Analysis; Training; cancer therapy; data integrity; data management; design; improved; longitudinal analysis; meetings; oncology; operation; prevent; protocol development; sound; statistical center; statistics; therapy outcome; translational study

DESCRIPTION (Provided by applicant): The mission of the Southwest Oncology Group (SWOG) is to conduct clinical trials to prevent and treat cancer in adults, and to improve the quality of life for cancer survivors. The mission is accomplished through the mutual efforts ofthe Group Chair's Office, the Operations Office, the Statistical Center and the dedicated oncology professionals in the institutions of the Group. The Statistical Center contributes to the mission of the Group though the following key activities: 1) Participation in protocol development, emphasizing statistically sound study designs; 2) Collection, review, manage and store data from Group studies, and to follow sound quality control procedures which ensure the integrity of data evaluations; 3) Development and maintenance of electronic applications to support the research and goals of the Southwest Oncology Group, including data collection, data management, data retrieval and analysis; 4) Analysis, interpretation and publication of results from ail Southwest Oncology Group studies; 5) Performance of methodologic research to address ongoing design and analysis issues important to the conduct of cancer clinical trials and to ancillary biologic studies; 6) Participation in training of new Clinical Research Associates (CRAs) and of Young Investigators in the Group. Biostatisticians and Data Coordinators educate investigators, nurse oncologists and CRAs in statistical analysis, research design and the utilization of the most advanced scientific and data management strategies; and 7) Collaboration with the Group Chair and other investigators in the Group to improve the quality of clinical trials through the use of improved data collection forms, reproducible data definitions and economical data flow, and efficient use of Statistical Center resources.

描述（由申请人提供）：西南肿瘤小组（SWOG）的使命是开展成人癌症预防和治疗的临床试验，并改善癌症幸存者的生活质量。这一使命是通过集团主席办公室、运营办公室、统计中心和集团机构中敬业的肿瘤学专业人员的共同努力来完成的。统计中心通过以下主要活动为小组的使命做出贡献：1)参与方案制定，强调统计上合理的研究设计；2)收集、审核、管理和存储集团研究数据，并遵循完善的质量控制程序，确保数据评估的完整性；3)开发和维护电子应用程序，以支持西南肿瘤集团的研究和目标，包括数据收集，数据管理，数据检索和分析；4)分析、解释和发表西南肿瘤组所有研究结果；5)进行方法学研究，以解决对癌症临床试验和辅助生物学研究进行重要的持续设计和分析问题；6)参与集团新入职临床研究助理（CRAs）和青年研究员的培训。生物统计学家和数据协调员在统计分析、研究设计和使用最先进的科学和数据管理策略方面教育调查人员、肿瘤学护士和CRAs；7)与小组主席和小组其他研究人员合作，通过使用改进的数据收集形式、可重复的数据定义和经济的数据流，以及有效利用统计中心资源，提高临床试验的质量。