Administrative Core for SWOG SDMC

SWOG SDMC 的管理核心

• 批准号: 10643702
• 负责人: Michael L. LeBlanc
• 金额: $ 141.3万
• 依托单位: FRED HUTCHINSON CANCER CENTER
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-04-17 至 2025-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10643702
• 关键词: Advisory Committees; Area; Biometry; Child; Clinical Data; Clinical Medicine; Clinical Sciences; Clinical Trials; Clinical Trials Design; Collaborations; Communities; Data; Data Analyses; Data Coordinating Center; Decision Making; Development; Ensure; Faculty; Fred Hutchinson Cancer Research Center; Genomics; Homes for the Aged; Hospitals; Immunotherapy; Leadership; Methods; Monitor; NCI Center for Cancer Research; National Clinical Trials Network; Research; Research Methodology; Research Personnel; Safety; Southwest Oncology Group; Statistical Methods; anticancer research; biobank; biological specimen archives; clinical development; clinical trial analysis; data management; data science management; data sharing; design; interest; meetings; member; multidimensional data; novel; organizational structure; precision medicine; programs; statistics; translational medicine; user-friendly; working group

Project Summary/Abstract Administrative Core The SWOG SDMC Administrative Core is the home of the senior administrative leadership team of the SDMC; it provides integration between the statistics and data management components. The senior administrative team (in partnership with the SWOG Group Chair and NCI) sets priorities regarding the development of clinical trial designs, monitoring, and data management for SWOG within the NCTN. The SWOG SDMC is located at the Fred Hutchinson Cancer Research Center and Cancer Research And Biostatistics, which are both non-profit research organizations. The SDMC contributes to the collective management of the NCTN Program by participating in the NCI Scientific Steering Committees, associated Task Forces, Working Groups, and other NCI initiatives. In addition, the Administrative Core provides data from completed clinical trials in a timely and user-friendly format for public access. The staff help in the interpretation of clinical data and facilitate the approved use of NCTN program specimens archived by SWOG at the centralized biobank at Children's Nationwide Hospital. SDMC faculty and staff have extensive collaborations with other NCTN Network Groups for the design, conduct, and analysis of clinical trials. They also have significant collaborations with other NCI-sponsored programs, especially the NCORP program. The faculty contribute to new statistical methods developments for clinical trials design, data monitoring and analysis, and genomic analysis, which is useful within the NCTN and also widely applicable to the greater cancer research community. Areas of interest include new methods for precision medicine, immunotherapy studies, and high-dimensional data analysis.

项目摘要/摘要 管理核心 SWOG国资委行政核心是国资委高级行政领导班子的所在地； 它提供统计和数据管理组件之间的集成。高级行政团队 (与SWOG小组主席和NCI合作)确定临床试验开发的优先事项 NCTN内SWOG的设计、监控和数据管理。SWOG SDMC位于 弗雷德·哈钦森癌症研究中心和癌症研究与生物统计学，都是非营利性的 研究机构。 国家计委通过参与NCI科学计划，为NCTN计划的集体管理做出了贡献 指导委员会、相关工作组、工作组和其他NCI倡议。此外， Administration Core以及时且用户友好的格式向公众提供已完成临床试验的数据 进入。工作人员帮助解释临床数据，并促进NCTN计划的批准使用 标本由SWOG存档在全国儿童医院的中央生物库。 SDMC教职员工与其他NCTN网络小组在设计、实施、 以及对临床试验的分析。他们还与NCI赞助的其他项目进行了重要的合作， 尤其是NCORP计划。 该学院致力于临床试验设计、数据监测和统计方法的新发展。 分析和基因组分析，这在NCTN中是有用的，也广泛适用于更大的癌症 研究社区。感兴趣的领域包括精确医学的新方法，免疫疗法研究，以及 高维数据分析。