Cyano-Map: Linking cyanobacteria metrics and human health

Cyano-Map：将蓝藻指标与人类健康联系起来

• 批准号: 8372518
• 负责人: Nathan Torbick
• 金额: $ 14.8万
• 依托单位: APPLIED GEOSOLUTIONS, LLC
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-08-15 至 2013-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8372518
• 关键词: Acute; Advocacy; Alanine; Algorithms; Amyotrophic Lateral Sclerosis; Anabaena; Architecture; Binding; Collaborations; Communities; Consult; Cyanobacterium; Data; Data Set; Development; Fees; Frequencies; Fresh Water; Goals; Health; Health Hazards; Health Professional; Human; Internet; Link; Maps; Marketing; Medical center; Methods; Metric; Microcystis; Monitor; N-Methyl-D-Aspartate Receptors; Names; Non-Essential Amino Acid; Outcome; Parkinson Disease; Phase; Property; Proteins; Provider; Public Health; Research; Resolution; Risk; Science; Services; Small Business Innovation Research Grant; System; Time; Toxic effect; Toxin; United States National Aeronautics and Space Administration; United States National Institutes of Health; Water; climate change; commercialization; e-commerce; feeding; harmful algal blooms; innovation; nervous system disorder; protein misfolding; prototype; remote sensing; sensor; tool; water quality

DESCRIPTION (provided by applicant): Research at the intersection of limnology and public health is showing that toxins produced from cyanobacteria act as an environmental trigger for Amyotrophic Lateral Sclerosis (ALS) commonly known as Lou Gehrig's Disease. Additional linkages are being made between cyanobacteria and Parkinson's and several acute illnesses and neurological disorders. A primary obstacle in advancing our understanding of linkages between cyanobacteria blooms, toxicity, and human health is water quality information on the presence, extent, magnitude, and intensity of these harmful algal blooms in freshwater bodies. Little to no exposure data is available to the public health community which has created an opportunity and innovation gap. Remote sensing science has now advanced to the point where operational assessment of cyanobacteria and water quality is feasible. The innovation of this NIH SBIR Phase 1 is the development of an operational cyanobacteria indicator tool (Cyano-Map) that utilizes NASA satellite remote sensing platforms and state-of-the-art geosciences methods. Cyano-Map will be capable mapping and monitoring phycocyanin (PC) abundance and cyanobacteria (i.e., microcystis, anabaena, and planktothrix) over space and time for inland waters. Cyano-Map will utilize multiple NASA platforms to extract the strengths of multiple sensors for the optimal spatial, temporal, spectral and radiometric resolutions. PUBLIC HEALTH RELEVANCE: Indicators and risk maps for cyanobacteria blooms in water systems and mapping environmental triggers for ALS and Parkinson's Disease.

描述（由申请人提供）：湖泊学和公共卫生交叉领域的研究表明，蓝藻产生的毒素是肌萎缩侧索硬化症（ALS）（俗称卢伽雷氏病）的环境触发因素。蓝藻与帕金森氏症以及几种急性疾病和神经系统疾病之间也存在更多联系。推进我们对蓝藻水华、毒性和人类健康之间联系的理解的一个主要障碍是有关淡水水体中这些有害藻华的存在、范围、规模和强度的水质信息。公共卫生界几乎无法获得暴露数据，这造成了机会和创新差距。遥感科学现已发展到可以对蓝藻和水质进行操作评估的程度。 NIH SBIR 第一阶段的创新是开发了一种可操作的蓝藻指示工具（Cyano-Map），该工具利用了 NASA 卫星遥感平台和最先进的地球科学方法。 Cyano-Map 将能够在空间和时间上绘制和监测内陆水域藻蓝蛋白 (PC) 丰度和蓝细菌（即微囊藻、鱼腥藻和浮游藻）。 Cyano-Map 将利用多个 NASA 平台来提取多个传感器的优势，以获得最佳的空间、时间、光谱和辐射分辨率。 公共卫生相关性：水系统中蓝藻大量繁殖的指标和风险图，以及绘制 ALS 和帕金森病的环境触发因素图。

项目成果

Assessing Cyanobacterial Harmful Algal Blooms as Risk Factors for Amyotrophic Lateral Sclerosis.

• DOI: 10.1007/s12640-017-9740-y
• 发表时间: 2018-01
• 期刊: Neurotoxicity research
• 影响因子: 3.7
• 作者: Torbick N;Ziniti B;Stommel E;Linder E;Andrew A;Caller T;Haney J;Bradley W;Henegan PL;Shi X
• 通讯作者: Shi X

Mapping amyotrophic lateral sclerosis lake risk factors across northern New England.

• DOI: 10.1186/1476-072x-13-1
• 发表时间: 2014-01-02
• 期刊: International journal of health geographics
• 影响因子: 4.9
• 作者: Torbick N;Hession S;Stommel E;Caller T
• 通讯作者: Caller T