Scientific Integrity in Community-Based Participatory Research

描述(由申请人提供)：基于社区的参与性研究(CBPR)强调社区参与研究的所有方面的重要性，包括研究问题的定义、数据收集和分析以及结果的应用。CBPR还强调教育和纠正社区合作伙伴、研究人员和参与者之间知识不平衡的重要性。CBPR框架被认为促进了对疾病和治疗结果发生的社会背景的更好的科学了解，从而为与之相关的问题提供了更有效和文化上量身定制的解决方案。到目前为止，CBPR的大部分研究和文献侧重于其优点、社区伙伴和研究人员在努力合作时遇到的困难，以及改进这种合作和更好地确保项目成功和传播调查结果的方法。对CBPR研究完整性保证的关注由来已久，并与与不同领域、学科、文化和社区相关的各种规范和惯例有关。缺乏系统地检查CBPR科学行为的潜在威胁的原创性研究，这项探索性研究将评估CBPR项目的广泛样本，涉及社区成员和组织、医疗保健提供者(护士、医生和其他人)、基于实践的研究网络(PBRN)和传统学术研究机构的联盟。这个项目的具体目标是：(1)描述社区成员和组织、医疗保健提供者、PBRN成员和学术研究人员关于可能影响CBPR项目科学完整性的目的、方法和预期结果的知识和理解；(2)描述影响CBPR项目科学严谨性的结构性因素，包括财政资源的可用性、数据收集和分析工具，或CBPR团队成员研究培训的不平衡；以及(3)确定将增加和保持CBPR研究完整性的教育内容。这项R21探索性研究的结果将有助于开发标准的CBPR培训模块，供社区成员和组织、医疗保健提供者以及参与CBPR项目的学术研究人员使用。该项目将通过系统地调查影响CBPR中研究完整性的因素，并开发应对研究完整性威胁的方法，来解决对CBPR科学价值的担忧。在实现其目标的过程中，该项目将确定将负责任的行为标准纳入CBPR以确保研究完整性的方法。这些方法将有助于提高CBPR结果的可靠性和有效性，从而更有意义和有效地参与社区参与的翻译科学。

DESCRIPTION (provided by applicant): Community-based participatory research (CBPR) emphasizes the importance of community participation in all aspects of research, including the definition of research questions, data collection and analysis, and application of findings. CBPR also emphasizes the importance of education and rectification of knowledge imbalances between community partners, researchers, and participants. The CBPR framework has been credited with facilitating better scientific understanding of the social context in which disease and treatment outcomes occur and, thereby, more effective and culturally tailored solutions to problems associated with them. To date, much of the CBPR research and literature focuses on its merits, the difficulties community partners and researchers encounter in their efforts to cooperate, and methods to improve that cooperation and better ensure project success and dissemination of findings. Concern for assurance of CBPR research integrity is long standing and connected to the variety of norms and conventions associated with the diverse fields, disciplines, cultures, and communities involved. Original research that systematically examines potential threats to the scientific conduct of CBPR is lacking and this exploratory study will evaluate potential threats to CBPR integrity across a broad sample of CBPR projects involving coalitions of community members and organizations, healthcare providers (nurses, physicians, and others), Practice Based Research Networks (PBRNs), and traditional academic research institutions. The specific aims of this project are: (1) to delineate knowledge and understanding among community members and organizations, healthcare providers, members of PBRNs, and academic researchers about purposes, methods, and desired consequences that may affect the scientific integrity of CBPR projects; (2) to delineate structural factors that affect the scientific rigor of CBPR projects, including availability of financial resources, data collection and analysis tools, or imbalances in research training of CBPR team members; and (3) to determine educational content that will increase and maintain CBPR research integrity. The results of this R21 exploratory study will facilitate development of standard CBPR training modules to be utilized by community members and organizations, health care providers, and academic researchers engaged in CBPR projects. This project will address concerns about the scientific merits of CBPR by systematically investigating the factors that influence research integrity in CBPR and developing methods to address threats to research integrity. In accomplishing its aims, this project will identify methods by which standards of responsible conduct may be incorporated into CBPR to ensure research integrity. These methods will facilitate increased reliability and validity of CBPR findings, and, thereby, more meaningful and effective community-engaged, translational science.