Administrative Core

行政核心由两个主要职能单位组成--执行单位和数据 管理、统计和信息技术(DMS/IT)股。执行单位的目标是 1)提供全面的科学和规划领导和指导，2)监督和协调 项目1和2的活动，3)确保所有 单位和调查人员，4)协调和监督项目财政资源的管理， 以及5)促进和确保计划项目遵守相关的联邦、大学和IRB 要求。数据管理、统计和信息技术(DMS/IT)股的目标是 至6)提供能够支持交互的最先进的数据管理系统和方法 多个参与调查人员的项目，7)提供一套在线资源和交流 促进学术交流、与距离无关的协作、信息 传播和具体项目培训，以及8)提供设计、建模、数据方面的统计专门知识 分析、统计编写和开发与执行 项目1和项目2。 与项目1和2的具体目标有关，临床和标本核心将招聘大量 研究参与者的数量，每个人都将为实验室评估贡献临床标本。 项目1将生成参与者的流行病学和行为数据，而项目2将生成 实验室数据采用临床标本。行政核心将在协调方面发挥核心作用 为实现这些机构的科学使命所需的行政、财政和人员支持 并促进它们之间的协同作用。行政核心也将是 在管理来自这些项目的大量数据和进行复杂的 提供可靠和有效结论所需的分析。

The Administrative Core consists of two major functional units - the Executive Unit and the Data Management, Statistics, and Information Technology (DMS/IT) Unit. The Aims of the Executive Unit are to 1) provide overall scientific and programmatic leadership and direction, 2) oversee and coordinate the activities of Projects 1 and 2, 3) ensure reliable exchange of information and collaboration among all the units and investigators, 4) coordinate and oversee management of the Program Project's fiscal resources, and 5) promote and ensure the Program Project's adherence to relevant federal, University, and IRB requirements. The Aims of the Data Management, Statistics, and Information Technology (DMS/IT) Unit are to 6) provide a state-of-the-art data management system and methods capable of supporting the interactive projects of multiple participating investigators, 7) provide a set of online resources and communications technologies that facilitate scholarly exchange, distance-independent collaboration, information dissemination and project-specific training, and 8) provide statistical expertise in design, modeling, data analysis, statistical writing, and the development of novel methodologies as related to the execution of Projects 1 and 2. Related to the specific aims of Project 1 and 2, the Clinical and Specimen Core will recruit a substantial number of study participants, each of whom will contribute clinical specimens for laboratory evaluation. Project 1 will generate epidemiological and behavioral data on the participants, while Project 2 will generate laboratory data using the clinical specimens. The Administrative Core will play a central role in coordinating the administrative, fiscal and personnel support required to achieve the scientific mission of these components and fostering the synergistic interaction among them. The Administrative Core will also be critical in managing the extensive amount of data from these projects and conducting the sophisticated analyses necessary to provide robust and valid conclusions.