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Shotgun Lipidomics and Alterations in Sphingolipidomes in Alzheimer's Diseases

Shotgun Lipidomics and Alterations in Sphingolipidomes in Alzheimer's Diseases
阿尔茨海默病中的鸟枪脂质组学和鞘脂组的改变
批准号：
8183807
负责人：
Xianlin Han
金额：
$51.36万
依托单位：
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE
依托单位国家：
美国
项目类别：
财政年份：
2007
资助国家：
美国
项目状态：
已结题
起止时间：
2007-09-01 至 2012-07-31
来源：
https://reporter.nih.gov/project-details/8183807
关键词：
Acyl Coenzyme AAddressAgingAlzheimer&aposs DiseaseBiochemicalBiochemical PathwayBioinformaticsBiological MarkersBrainBrain regionCell DeathCeramidesCerebrospinal FluidComplexDataDevelopmentDiabetes MellitusDiseaseEarly DiagnosisEthanolaminesEventFingerprintFoundationsFunctional disorderGangliosidesGlycerophospholipidsHumanIndividualLactosylceramidesLinkLipidsMapsMass Spectrum AnalysisMetabolic PathwayMethodsMinorMolecularMultivariate AnalysisMyelinNerve DegenerationObesityPathogenesisPathologyPathway interactionsPharmaceutical PreparationsPlayProcessPsychosineReproducibilityResearchResearch PersonnelRoleSamplingSeveritiesShotgunsSolidSphingolipidsSphingosineStagingStructureSulfoglycosphingolipidsSynapsesTechnologyTissuesanalogbasebrain tissueceramide 1-phosphatecomputerized data processinggray matterhuman tissueinsightinterestknockout genelipid metabolismmetabolomicsnovelnovel therapeutic interventionprogramssphingosine phosphorylcholinewhite matter

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