2012 International Conference on Gram-positive Pathogens

描述（由申请方提供）：革兰氏阳性病原体引起的感染，包括金黄色葡萄球菌、化脓性链球菌、艰难梭菌和屎肠球菌等，是我们社会的负担，导致显著的发病率和死亡率。2012年国际革兰氏阳性病原体会议（ICGPP）旨在通过促进研究革兰氏阳性致病机理和生物学多个方面的研究人员之间的互动来更好地了解这些细菌。我们正在申请资金，以部分支持将于2012年10月7日至10日在内布拉斯加州奥马哈举行的2012年ICGPP。我们已经确保了五位国际公认的主题演讲者的参与，他们将专注于细菌代谢在致病机制调节中的功能以及宿主与病原体之间的界面。全球物理学基础设施国际委员会的一个重要优先事项是博士前和博士后受训人员的积极参与;将为那些愿意作口头报告的年轻科学家提供一切便利。最终，本次会议的目标是通过产生新的合作来拓宽我们对革兰氏阳性致病机制和生物学的理解，并通过研究这些相关病原体中的类似系统来获得新的见解。 公共卫生相关性：革兰氏阳性病原体国际会议（ICGPP）提供了一个论坛，研究革兰氏阳性病原体发病机制和生物学多个方面的研究人员可以互动和分享想法，以提高对这些重要病原体的普遍理解。这些相互作用将促进新的想法和合作，最终开发新的治疗方案来治疗这些有时是毁灭性的感染。

Description (as provided by the applicant): Infections caused by gram-positive pathogens, including Staphylococcus aureus, Streptococcus pyogenes, Clostridium difficile, and Enterococcus faecium, among others, are a burden on our society causing significant morbidity and mortality. The 2012 International Conference on Gram-Positive Pathogens (ICGPP) seeks to better understand these bacteria through fostering interactions between investigators studying multiple aspects of gram-positive pathogenesis and biology. We are applying for funds to support, in part, the 2012 ICGPP, which will be held in Omaha, NE on October 7-10, 2012. We have secured the participation of five internationally recognized keynote speakers that will focus on the function of bacterial metabolism in the regulation of pathogenesis and the interface between host and pathogen. A significant priority of the ICGPP is the active participation of pre- and post-doctoral trainees; every accommodation will be given to those junior scientists who prefer to give oral presentations. Ultimately, the goal of this conference is to broaden our understanding of Gram- positive pathogenesis and biology through the generation of new collaborations and to gain new insights through the study of similar systems in these related pathogens. Public Health Relevance: The International Conference on Gram-Positive Pathogens (ICGPP) provides a forum where investigators studying multiple aspects of gram-positive pathogenesis and biology can interact and share ideas to enhance the general understanding of these important pathogens. These interactions will foster new ideas and collaborations to ultimately develop novel therapeutic regimens to treat these sometimes devastating infections.