2012 Biology of Spirochetes Gordon Research Conference

产品说明： 本申请要求对螺旋体生物学会议的部分支持，作为戈登研究会议系列的一部分，将于2012年1月22日至27日在加利福尼亚州文图拉举行。本次会议的目的是聚集螺旋体生物学所有领域最活跃和最富有成效的研究人员，分享该领域前沿的研究进展，并为思想的交叉施肥提供论坛。本次会议的总体目标是提高对这些不寻常的细菌及其引起的疾病的理解。在这个技术上具有挑战性的领域引入和指导新的研究人员仍然是一个紧密相关的目标。这次会议的具体目标是召集50多名具有包括几个致病螺旋体属的专门知识的科学家，共有175名与会者，在一个非正式和高度互动的环境中举行为期五天的会议，以促进思想交流。会议计划包括9个会议，涵盖了广泛的基础和临床相关主题，包括免疫机制，螺旋体疾病的流行病学和发病机制，螺旋体感染因子的进化，生态学和传播，以及这些独特细菌的结构，代谢，遗传学和分子生物学。下午的海报会议将包括所有与会者的积极参与。每一次会议的邀请和确认发言者包括领先的科学家和富有成效的研究螺旋体的新调查人员。此外，每届会议的发言者中约有四分之一将从提交的摘要中选出，以确保更多年轻科学家的相关前沿研究被纳入其中。已经有意识地作出努力，并将扩大努力范围，鼓励研究生和早期职业研究人员的参与，确保性别平衡，并包括少数民族和残疾人的参与。这一应用的意义在于，本次戈登研究会议将为致力于这些多样化和医学相关细菌的国际研究界成员提供一个独特的交流机会。这一应用的健康相关性在于，随后的讨论将促进有助于预防、诊断和控制严重、研究不足和新出现的螺旋体疾病的研究，这些疾病困扰着世界各地越来越多的人。 公共卫生相关性： 本次会议致力于讨论所有医学重要和生物相关的螺旋体的前沿基础，应用和转化研究，这些螺旋体包括一组独特但多样的细菌。许多螺旋体是病原体，并引起各种人类和动物疾病，包括梅毒、钩端螺旋体病、莱姆病、回归热、牙周病和痢疾。在这次戈登研究会议上产生的讨论将促进有助于改善螺旋体感染的预防，诊断和控制的研究。会议的非正式、以讨论为导向的环境促进了所有与会者之间的宝贵互动。

DESCRIPTION: This application requests partial support for a meeting on the Biology of Spirochetes as part of the Gordon Research Conference series to be held in Ventura, CA, January 22-27, 2012. The purpose of this conference is to assemble the most active and productive investigators in all areas of spirochete biology to share research advances at the frontier of the field and provide a forum for cross-fertilization of ideas. An overarching goal of this conference is to improve understanding of these unusual bacteria and the diseases they cause. The introduction and mentoring of new researchers in this technically challenging field remains a tightly associated goal. The specific aim of this meeting will be to bring together over 50 scientists with expertise encompassing several genera of pathogenic spirochetes, with a total of 175 participants, for a five-day conference in an informal and highly interactive environment that fosters the exchange of ideas. The conference program consists of 9 sessions encompassing a broad array of basic and clinically relevant topics, including mechanisms of immunity, epidemiology and pathogenesis of spirochetal diseases, evolution, ecology and transmission of spirochetal infectious agents, and the structure, metabolism, genetics and molecular biology of these unique bacteria. Afternoon poster sessions will include active participation by all attendees. Invited and confirmed speakers in every session include both leading established scientists and productive new investigators studying spirochetes. In addition, approximately one quarter of the speakers in each session will be selected from submitted abstracts to assure inclusion of pertinent cutting-edge research by more junior scientists. A conscious effort has been made and will be extended to encourage participation by graduate students and early career researchers, to assure gender balance, and to include participation by minorities and persons with disabilities. The significance of this application is that this Gordon Research Conference will provide a unique opportunity for cross-fertilization of ideas by members of the international research community working on these diverse and medically relevant bacteria. The health relatedness of this application is that the ensuing discussions will promote research contributing to the prevention, diagnosis and control of the serious, understudied and emerging spirochetal diseases that afflict a large and growing number of people around the world. PUBLIC HEALTH RELEVANCE: This conference is devoted to discussions of leading edge fundamental, applied and translational research of all medically important and biologically relevant spirochetes, which comprise a unique but diverse group of bacteria. Many spirochetes are pathogens and cause a variety of human and animal diseases, including syphilis, leptospirosis, Lyme borreliosis, relapsing fever, periodontal disease and dysentery. The discussions generated at this Gordon Research Conference will promote research contributing to improved prevention, diagnosis and control of spirochetal infections. The informal, discussion-oriented environment of the conference fosters valuable interactions between all participants.