2008 Spirochetes Gordon Research Conference

摘要/摘要 第八届戈登螺旋体生物学研究大会将在北京举行 2008年1月至2月，加利福尼亚州文图拉。螺旋体生物学会议是 独一无二。这是唯一一次专门讨论基础研究的国际会议。 在所有医学上重要的和生物上相关的螺旋体中，有一组独特的真细菌。 许多螺旋体是病原体，它们会引起各种疾病，包括梅毒、莱姆病 疾病，回归热，钩端螺旋体病，牙周病，牛和猪的数字皮炎 和人类的痢疾。从历史上看，螺旋体一直很难研究。这些 细菌通常具有挑剔的营养要求，许多还没有成功。 体外培养。几种螺旋体的遗传操作和突变分析方法 物种是不存在的。在致力于不同项目的小组之间交换意见的机会 螺旋体是过去各次会议的最大好处之一，特别是在 基因操作的新技术和不断扩大的功能基因组学领域。这个 疏螺旋体遗传进展及基因组序列可用性的应用 Burgdorferi、梅毒螺旋体、齿密螺旋体和钩端螺旋体新的测序项目。 提供了丰富的新信息。综合起来，这些进步正在被整合到 目前正在对它们的生理、结构、发病机制和免疫生物学进行研究 细菌。 之前的每一届螺旋体生物学会议都非常成功， 受到与会嘉宾好评，打造新合作，提供展示论坛 对这些细菌进行最先进的研究，并帮助设定新的研究方向。如中所示 在以往的会议上，我们预计2008年会议的出席人数将达到 150名教职员工、研究生、博士后研究员和工业科学家。广谱 代表不同研究兴趣、地理位置和资历的科学家将是 受邀出席。2008年，将作出特别努力，确保青年学生出勤率高。 调查人员(研究生、博士后和初级教员)，并实现公平的 与会者的性别和种族分布情况。口头和海报演示文稿如下 组织提供许多讨论、思想交流和 合作的发展。请求美国国立卫生研究院提供资金以 部分抵消了参赛研究生的旅费和报名费， 研究员和初级教职员工。

Summary/Abstract The eighth Gordon Research Conference on the Biology of Spirochetes will be held in January-February 2008 in Ventura, California. The Biology of Spirochetes Conference is unique. This is the only ongoing international meeting devoted to discussions on basic research of all medically important and biologically relevant spirochetes, a unique group of Eubacteria. Many spirochetes are pathogens, and they cause a variety of diseases, including syphilis, Lyme disease, relapsing fever, leptospirosis, periodontal disease, digital dermatitis of cattle, and swine and human dysentery. Historically, spirochetes have been very difficult to study. These bacteria often have fastidious nutritional requirements, and many have yet to be successfully cultured in vitro. Methods for genetic manipulation and mutational analysis of several spirochete species do not exist. The opportunity for exchange of ideas among groups working on different spirochetes has been one of the greatest benefits of past conferences, particularly in the area of new techniques for genetic manipulation and the expanding field of functional genomics. The application of genetic advancements and the availability of genomic sequences for Borrelia burgdorferi, Treponema pallidum, T. denticola, and new sequencing projects in Leptospira spp. are providing a wealth of new information. Combined, these advances are being integrated into ongoing studies on the physiology, structure, pathogenesis, and immunobiology of these bacteria. Each of the previous Biology of Spirochetes conferences has been highly successful, receiving high praise by attendees, forging new collaborations, providing a forum for presenting state-of-the-art research on these bacteria, and helping to set new research directions. As in previous conferences, we expect attendance at the 2008 conference to reach the maximum of 150 faculty, graduate students, postdoctoral fellows, and industrial scientists. A broad spectrum of scientists representing different research interests, geographic locations, and seniority will be invited to attend. For 2008, special efforts will be made to ensure strong attendance of young investigators (graduate students, post-docs, and junior faculty), and to achieve an equitable distribution in gender and ethnicity of attendees. The oral and poster presentations are organized to provide many opportunities for discussion, the exchange of ideas, and development of collaborations. Funding from the National Institutes of Health is requested to partially offset the travel and registration expenses of the participating graduate students, fellows, and junior faculty members.