Rapid Pathogen Detection using Super-Sensitive Multiplexing Nanophotonic Probes

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Responding to an urgent need to advance rapid molecular diagnostics, this project aims to explore new photonics and biochemistry approaches to DNA recognition. It is anchored on proprietary light-emitting nanodots which have single-molecule sensitivity in conjunction with tunable optical identities. The project aims to develop a multiplexing reagent library of DNA probes to sense trace DNA molecules and to recognise multiple pathogens in a single assay. This innovation aims to create a hybrid-Polymerase Chain Reaction (PCR) technology platform for current industry-standard pathogen detection tests. The outcomes of the project aim to enable DNA based pathogen diagnostics within 90 minutes, four times faster than the current tests.