Los Angeles Stroke Prevention/Intervention Research Program in Health Disparities

描述（由申请人提供）：洛杉矶中风预防/干预健康差异研究项目是由加州大学洛杉矶分校、洛杉矶县安全网系统中的四个医疗中心、健康非裔美国人家庭和来自多个社区组织的代表合作开展的，这些组织为洛杉矶盆地的低收入少数群体社区提供服务。在这个美国种族最多样化的国家，我们提出了一个多学科，高度协作的项目，以创建和测试可持续的干预措施，以减少或消除中风发生的种族和民族差异，并产生关于这种差异机制的新知识。项目一通过社区卫生工作者和流动卫生技术建立了一个强大的社区组成部分，以创建一个全面的慢性护理模式干预措施，并将在洛杉矶县安全网中最近出现的500名中风患者中进行相对于常规护理的测试。成本分析和形成性评价将指导财务可持续性计划的制定。项目二将阐明

DESCRIPTION (provided by applicant): The Los Angeles Stroke Prevention/ Intervention Research Program in Health Disparities is a partnership of UCLA, four medical centers in the Los Angeles County safety net system, Healthy African American Families, and representatives from multiple community organizations serving low-income minority communities that span the Los Angeles basin. In this most diverse county in the US in race/ethnicity, we propose a multi-disciplinary, highly collaborative Program to create and test sustainable interventions to reduce or eliminate racial and ethnic disparities in the occurrence of stroke, and to generate new knowledge about mechanisms for such disparities. Project I creates a strong community-based component with community health workers and mobile health technology to create a full-fledged Chronic Care Model intervention that will be tested relative to usual care in 500 patients with a recent stroke seen in the Los Angeles County safety net. A cost analysis and a formative evaluation will guide development of a financial sustainability plan. Project II will elucidate the role of novel biological and social risk factors for stroke risk and trends over time, in a nationa data set. Project III builds on an existing close partnership with the City of Los Angeles Department of Aging to develop and test a culturally-tailored behavioral stroke risk factor reduction/walking intervention - delivered by senior center staff-with 240 high risk seniors from Korean, Chinese, African-American and Hispanic racial/ethnic groups. Four cores include an Administrative Core A that supports all three projects; a Research Education and Training Core B that will recruit, retain, and develop stroke disparities-relevant curriculum for academic researchers, community research support personnel and other community stake holders; a Biomarker Collection and Analysis Core C to support Project I and III biomarker data collection, consulting for all three projects, and development of educational programming on biomarkers; and a Community Engagement, Outreach, and Dissemination Core D that supports and interacts with all three projects by promoting and sustaining community-academic partnerships through bidirectional knowledge sharing and by creating strategies for disseminating advances in knowledge about stroke prevention disparities research through outreach to affected communities locally and nationally. PUBLIC HEALTH RELEVANCE: A coordinated effort of researchers and community partners is needed to reduce or eliminate the higher rates of stroke among low-income Latinos, African-Americans, and Asian Americans in underserved communities. The Los Angeles Stroke Prevention/Intervention Program in Health Disparities will carry out research, develop education programs, and share and learn from the community to meet this goal.