CHILDREN'S LEARNING BRAIN METER

描述(由申请人提供)：目前，对儿童认知大脑功能的测量是通过重复的人工心理测量测试进行的。从这些措施中得出的推论对儿童实际的真实世界学习能力的推论可能是有限的。因此，我们建议实现第一个自动系统，方便和准确地测量参与学习练习和游戏的儿童与学习相关的神经电脑电信号。在我们实验室最近的技术和科学进步的基础上，拟议的设备将向教育研究人员和临床医生提供有关儿童在学习过程中区域皮质大脑激活的信息。这些信息将有助于前者更准确地评估教育策略和课件，后者有助于评估儿童在功能关键和发展必要的学习过程中的神经认知能力。在第一阶段，我们论证了拟议系统的科学和技术可行性。特别是，我们说明了参与复杂计算机任务(如玩电子游戏)的儿童的区域皮质激活的神经电脑电信号可以被有效地监测。第二阶段的工作将扩展可行性研究，并将在正常和学习困难的临床人群中开发、测试、改进和验证儿童在基于计算机的学习活动中大脑功能的自动脑电测量。这些措施将被纳入一个高通量的自动化测试系统。该系统将使对儿童基于计算机的学习的系统研究成为可能，初步规范的制定将为该系统用于临床评估和改进治疗干预措施铺平道路。这项技术还可以在未来的“闭环”神经适应系统中发挥作用，该系统使用实时监测与任务相关的神经激活来提高课件和学习效率。与公共健康相关儿童学习脑电图仪是一种很有前途的新型自动化高通量技术，它可以在儿童坐在普通房间的办公桌前进行基于计算机的学习练习和游戏时测量大脑电信号。它将向教育研究人员和临床医生提供有关儿童在学习过程中大脑区域皮质激活的信息，否则无法获得。该系统将使对儿童基于计算机的学习的系统研究成为可能，初步规范的制定将为该系统用于临床评估和改进治疗干预措施铺平道路。

DESCRIPTION (provided by applicant): Currently, measurements of a child's cognitive brain function are made during repetitive, artificial psychometric tests. The generalization of inferences from such measures to a child's actual real-world learning ability may be limited. Accordingly, we propose to implement a first-of-its-kind automated system that conveniently and accurately measures learning-related neuroelectric EEG signals of children engaged in learning exercises and games. Building on recent technological and scientific advances in our lab, the proposed device will provide otherwise unavailable information to both educational researchers and to clinicians about a child's regional cortical brain activation during learning. Such information will help the former to more accurately evaluate educational strategies and courseware, and the later to assess a child's neurocognitive capabilities during the functionally critical and developmentally essential process of learning. During Phase I, we demonstrated the scientific and technical feasibility of the proposed system. In particular, we illustrated that neuroelectric EEG signals of regional cortical activation of children engaged in complex computerized tasks such as video game play could be validly monitored. The Phase II work will extend the feasibility study and will develop, test, refine, and validate automated EEG measures of a child's brain function during computer-based learning activities in both normative and learning-challenged clinical populations. The measures will be incorporated into a high-throughput automated testing system. This system will enable systematic research on computer-based learning for children, and development of preliminary norms will pave the way for the system to be used clinically to evaluate and refine therapeutic interventions. The technology could also be instrumental in future "closed-loop" neuroadaptive systems that use real time monitoring of task-related neural activation to improve courseware and learning efficiency. PUBLIC HEALTH RELEVANCE The Children's Learning Brain Meter is a promising new automated high-throughput technology that measures brain electrical signals as a child engages in computer-based learning exercises and games while sitting at a desk in an ordinary room. It will provide otherwise unavailable information to educational researchers and clinicians about a child's regional cortical brain activation during learning. This system will enable systematic research on computer-based learning for children, and development of preliminary norms will pave the way for the system to be used clinically to evaluate and refine therapeutic interventions.