analysis core - NINDS INSTIUTIONAL CENTER CORE GRANTS TO SUPPORT NEUROSCIENCE RES

分析核心 - NINDS 机构中心核心拨款支持神经科学研究

• 批准号: 8374968
• 负责人: Mark A. Mintun
• 金额: $ 22.08万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-09-20 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8374968
• 关键词: Brain imaging; Center Core Grants; Commit; Computer software; Data; Documentation; Four-dimensional; Funding; Goals; Image; Institution; Linux; Masks; Methods; Monitor; Movement; National Institute of Neurological Disorders and Stroke; Neurosciences; Neurosciences Research; Procedures; Reading; Recommendation; Research; Research Personnel; Resources; Running; Science; Software Tools; Structure; Time; Universities; Washington; Writing; imaging modality; operation; programs

In the last five years the NCCBI has supported the extensive expansion and documentation of a group of software tools termed the "4dfp suite". These programs read and write image data in 4dfp (or 4-dimensional floating point) format (x, y, z, time). The 4dfp format for image data was initially defined at WU in 1996 and is very similar to the more recent NlfTI format (htpp://nifti.nimh.nih.gov) except for certain header structures. The 4dfp suite includes an extensive set of binary executables and shell scripts (running under UNIX or Linux) that perform critical image algebra and analysis operations, e.g., filtering, registration, masking, etc. We will offer users the option of having all appropriate data undergo preprocessing immediately upon arrival at the CNDA (e.g., conversion of the reconstructed data from DICOM to the format used by the analysis software). All preprocessing will be monitored by the Analysis Core staff. As directed by the Steering Committee, the 4dfp suite of preprocessing software will be enhanced and modified by the Analysis Core staff programmers as necessary to support the specific needs of investigators. In addition, while most of what follows in this proposal refers to 4dfp procedures, we will also support established external packages (e.g., SPM, FSL, Freesurfer, and AFNI). Finally, a major advantage for NCCBI users is that all executables invoked by NCCBI pipelines are also available to those expert users who choose to create their own scripts. While the objectives are extremely broad and movement on nearly all the goals listed above will begin in the first two years of this next funding cycle, the resources of the Analysis Core will be considerable, especially when the additional funds and resources to be provided by Washington University are considered. A strength of this Core will be the ability to identify value; in new imaging methods as they arrive in the field and with the recommendation of the Steering Committee, commit resources for implementing these methods in our portfolio. IN this way we believe that establishment of the NCCBI Analysis Core will substantially benefit neuroscience research at our institution. Many of our NINDS funded users, listed below, would otherwise have no practical means of expanding, or optimizing, research imaging within their research agenda. Other users more established in imaging will be able to greatly augment their science by expanding their imaging research in new directions.

在过去的五年中，NCCBI支持了一组被称为“4dfp套件”的软件工具的广泛扩展和文档编制。这些程序以4dfp（或4维浮点数）格式（x, y, z，时间）读写图像数据。图像数据的4dfp格式最初是在1996年在WU上定义的，除了某些标题结构外，它与最近的NlfTI格式非常相似。4dfp套件包括一组广泛的二进制可执行文件和shell脚本（在UNIX或Linux下运行），它们执行关键的图像代数和分析操作，例如过滤、注册、屏蔽等。我们将提供