Quality Assurance Review Center

质量保证审查中心

• 批准号: 8322877
• 负责人: Thomas J. FitzGerald
• 金额: $ 7.28万
• 依托单位: UNIV OF MASSACHUSETTS MED SCH WORCESTER
• 依托单位国家: 美国
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-08-15 至 2012-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8322877
• 关键词: Accounting; Archives; Benchmarking; Breathing; Cancer Patient; Cancer Therapy Evaluation Program; Cancer and Leukemia Group B; Caring; Case Management; Clinical; Clinical Research; Clinical Trials; Clinical Trials Cooperative Group; Collaborations; Complex; Cooperative Group Program; Credentialing; Data; Data Quality; Development; Diagnostic Imaging; Diagnostic Imaging Program; Discipline; Electronics; Eligibility Determination; Ensure; Evaluation; Evaluation Reports; Funding; Goals; Grant; Guidelines; Image; Imaging technology; Individual; Institution; Instruction; Internet; Leadership; Malignant Neoplasms; Massachusetts; Medicine; Methods; Mission; Motion; Outcome; PET/CT scan; Patients; Performance; Positron-Emission Tomography; Process; Progress Reports; Protocols documentation; Publications; Radiation therapy; Radiology Specialty; Reporting; Research; Research Infrastructure; Research Personnel; Research Support; Resources; Role; Services; Source Code; Standardization; Technology; Time; Treatment outcome; Universities; Work; data acquisition; data format; data management; data sharing; digital; dosimetry; electronic data; image archival system; imaging modality; improved; medical schools; new technology; open source; programs; protocol development; quality assurance; response; standard of care; success; treatment planning

DESCRIPTION (provided by applicant): The Quality Assurance Review Center (QARC) has been funded by the NCI since 1980 to provide radiation therapy quality assurance services for multiple NCI funded cooperative groups. These services include acquisition and management of protocol required data, target volume and treatment dosimetry review, and reporting and archiving of the data and images. QARC will continue to promote participation and compliance in trials through interventional reviews and non-restrictive formats for data submission. QARC will support the expanding use of imaging and new imaging modalities in clinical trials and will participate in national initiatives on uniform standards. QARC will expand its capability to electronically receive, review, and archive both imaging and radiation therapy data and will support the incorporation of advanced technologies by developing appropriate protocol guidelines and credentialing strategies. These goals will increase the participation and compliance in clinical trials, resulting in faster answers to protocol questions. For over 25 years QARC has demonstrated that QA of radiation therapy improves protocol outcomes. Interventional review at the start of treatment reduces the number of protocol deviations, thereby helping to validate protocol results. This process will continue in the next grant cycle. A major goal of this proposal which will facilitate both interventional and final reviews is further development and expansion of QARC's ability to receive, review, and archive electronically transmitted data. Already facile with DICOM image handling, QARC will work with the diagnostic imaging committees of the cooperative groups and participate in national initiatives to standardize data formats and to promote the role of imaging in clinical trials. For treatment planning data, QARC has established the capability to review digital data through partnership in the Advanced Technology Consortium; this collaboration will continue as will further development of the open source code CERR application. As protocols become increasingly complex and image-driven, timely review by multiple experts is necessary. To fulfill this need, QARC will develop Web browser capability for real-time review using .net technology. To support the use of new technologies in clinical trials, QARC will develop, as it has in the past, templates for protocol guidelines and benchmarks for credentialing institutions in new technologies, which will likely include PET, PET/CT and methods that limit or account for motion during breathing. The mission of the Clinical Trials Cooperative Group Program is to improve the lives of cancer patients by finding better ways to treat, control and cure cancer. QARC's program will advance the radiation therapy and diagnostic imaging quality of these clinical trials. Overall standard of care of cancer patients will be improved.

描述（由申请人提供）：自1980年以来，NCI自1980年以来一直由NCI资助，为多个NCI资助的合作团体提供放射治疗质量保证服务。这些服务包括对协议所需数据的获取和管理，目标量和治疗剂量法审查以及数据和图像的报告和归档。 QARC将继续通过介入的审查和非限制性格式来促进参与和合规性，以提交数据提交。 QARC将支持在临床试验中扩大成像和新成像方式的使用，并将参与有关统一标准的国家计划。 QARC将扩大其能力，以电子接收，审查和存档成像和放射治疗数据，并通过制定适当的协议指南和凭证策略来支持高级技术的合并。这些目标将增加临床试验中的参与和依从性，从而更快地回答协议问题。 25年来，QARC已证明辐射疗法的质量检查可以改善方案结果。干预审查在治疗开始时减少了协议偏差的数量，从而有助于验证协议结果。这个过程将在下一个赠款周期继续。该提案将促进介入和最终审查的主要目标是QARC接收，审查和归档电子传输数据的能力的进一步发展和扩展。 QARC已经可以使用DICOM图像处理，将与合作团体的诊断成像委员会合作，并参与国家计划，以标准化数据格式并促进成像在临床试验中的作用。对于治疗计划数据，QARC已经建立了通过高级技术联盟中的合作伙伴关系来审查数字数据的能力。这项合作将继续进行，将进一步开发开源代码CERR应用程序。随着协议变得越来越复杂和以图像为导向，必须及时审查多个专家。为了满足这一需求，QARC将使用.NET技术开发Web浏览器功能，以实时审核。为了支持在临床试验中使用新技术，QARC将像过去一样开发QARC的模板，用于在新技术中为机构提供凭证的凭证，其中可能包括PET/CT，以及限制呼吸过程中运动的宠物/CT和方法。临床试验合作小组计划的任务是通过寻找更好的治疗，控制和治愈癌症的方法来改善癌症患者的生活。 QARC的计划将提高这些临床试验的放射疗法和诊断成像质量。癌症患者的总体护理标准将得到改善。