Imaging and Radiation Oncology Core (IROC) Group

影像和放射肿瘤学核心 (IROC) 小组

• 批准号: 8853251
• 负责人: Thomas J. FitzGerald
• 金额: $ 700万
• 依托单位: AMERICAN COLLEGE OF RADIOLOGY
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-05-26 至 2019-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8853251
• 关键词: American College of Radiology; American College of Radiology Imaging Network; Archives; Cancer and Leukemia Group B; Clinical; Clinical Research; Clinical Trials; Clinical Trials Cooperative Group; Clinical Trials Database; Clinical Trials Network; Communication; Communication Programs; Cooperative Group Program; Credentialing; Data; Data Collection; Data Set; Databases; Development; Disease; Ensure; Feedback; Future; Goals; Grant; Health; Image; Information Systems; Information Technology; Institution; Leadership; Malignant Neoplasms; Medicine; Methodology; Modality; National Clinical Trials Network; Outcome; Participant; Patients; Phase; Procedures; Process; Protocols documentation; Radiation Oncology; Radiation Therapy Oncology Group; Radiation therapy; Research; Research Infrastructure; Science; Secure; Services; Site; Southwest Oncology Group; Structure; Technical Expertise; Therapeutic; Uncertainty; Vision; Work; data management; digital imaging; effective therapy; image processing; innovation; member; operation; organizational structure; programs; quality assurance; trial design

DESCRIPTION (provided by applicant): The primary objective of the imaging and Radiation Oncology Core (IROC) Group is to provide scientific and technical expertise for incorporation of appropriate, integrated Quality Assurance (QA) and image data management for both imaging and radiotherapy (RT) in applicable trials conducted by the National Clinical Trials Network (NCTN) Program. The leading QA centers; RPC, QARC, RTOG QA, ITC, ACRIN and CALGB/SWOG Imaging Core lab, in the current NCI Cooperative Group Program have joined together to form the IROC Group, administratively organized through the American College of Radiology (ACR) Clinical Research Center. The creation of IROC capitalizes on existing infrastructure and expertise at QA Centers currently providing services to the NCI Cooperative Groups. Work flows, processes and information systems currently in place will be further enhanced taking the best practices and standards in an integrated vision. The interdependencies between imaging and RT will be synergized in this QA Group eliminating duplication of services and optimizing towards efficient and effective workflows. A major strength of IROC will be the development of consistent standard operating procedures for all imaging and RT aspects of the NCTN and to facilitate a seamless flow of imaging and RT patient case datasets across the network. IROC's organizational structure allows the delivery of a broad array of imaging and RT QA services including Site Qualification; Trial Design Support; Credentialing; Data Management (Pre- and Post- Review); and Case Review. An information technology infrastructure will be developed that harmonizes IROC services, data collection, assessment and management for the NCTN Groups' clinical trials. IROC will implement programs that assure consistent high quality imaging and RT planning/delivery across the NCTN participating sites. IROC members will collaborate with the NCTN disease/modality committees within each Network Group to provide an optimal and effective imaging and RT core service. IROC will analyze QA data obtained prospectively/retrospectively to further advance QA science. IROC will manage all aspects of QA for NCTN trials that includes imaging and/or RT with the shared goal to achieve the best possible trial outcomes.

描述（由申请人提供）：成像和辐射肿瘤学核心（IROC）组的主要目标是提供科学和技术专业知识，以在国家临床试验网络（NCTN）进行的适用试验中纳入适当的，集成的质量保证（QA）和图像数据管理（QA）和图像数据管理（RT）。领先的质量检查中心； RPC，QARC，RTOG QA，ITC，ACRIN和CALGB/SWOG Imaging Core Lab在当前的NCI合作小组计划中，已经组建了由美国放射学学院（ACR）临床研究中心进行行政组织的IROC集团。 IROC的创建资源是在当前为NCI合作团体提供服务的质量检查中心现有基础设施和专业知识上的资本。当前到位的工作流，流程和信息系统将进一步增强，以综合愿景中的最佳实践和标准。成像和RT之间的相互依存关系将在该质量检查组中取消，以消除复制服务并优化有效有效的工作流程。 IROC的主要优势将是为NCTN的所有成像和RT方面的一致标准操作程序开发，并促进整个网络上无缝的成像和RT患者病例数据集的无缝流。 IROC的组织结构允许提供广泛的成像和RT质量检查服务，包括网站资格；试用设计支持；证书；数据管理（审查前和审查）；和案例审查。将开发一个信息技术基础架构，以协调NCTN组临床试验的IROC服务，数据收集，评估和管理。 IROC将实施计划，以确保NCTN参与站点的一致的高质量成像和RT计划/交付。 IROC成员将与每个网络组内的NCTN疾病/模式委员会合作，提供最佳有效的成像和RT核心服务。 IROC将分析前瞻性/追溯获得的质量检查数据，以进一步推进质量检查科学。 IROC将管理QA的所有方面，用于NCTN试验，其中包括成像和/或RT，其共同目标以实现最佳的试验结果。