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Anti-topoisomerase drug action in yeast

Anti-topoisomerase drug action in yeast
酵母中的抗拓扑异构酶药物作用
批准号：
8332561
负责人：
JOHN L NITISS
金额：
$15.88万
依托单位：
UNIVERSITY OF ILLINOIS AT CHICAGO
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
项目状态：
已结题
起止时间：
1997-06-01 至 2015-01-31
来源：
https://reporter.nih.gov/project-details/8332561
关键词：
ATPase DomainAffectAffinityAllelesAntineoplastic AgentsBindingBiochemicalBiologicalBiological AssayBiological ModelsC-terminalCleaved cellClinicalCollaborationsComplexDNADNA DamageDNA SequenceDNA TopoisomerasesDimerizationDoxorubicinDrug Delivery SystemsDrug HypersensitivityDrug InteractionsDrug effect disorderEnzymesEtoposideGeneticGoalsGrantHumanIn VitroLeadMeasurementMediatingModelingMutationNew AgentsOrganismPharmaceutical PreparationsPhenotypePlayPoisonProcessPropertyProteinsReactionReagentResolutionRoleSaccharomyces cerevisiaeStructureSystemTOP2A geneTestingTopoisomeraseTopoisomerase IITransducersWorkX-Ray CrystallographyYeastsdesigndrug mechanismdrug sensitivitydrug structureinsightmutantnovelpublic health relevanceresearch studysmall moleculestructural biologythree dimensional structuretool

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