Defective p53 synthesis following DNA damage and cancer development

DNA 损伤和癌症发展后 p53 合成缺陷

• 批准号: 8369382
• 负责人: Da-Qing Yang
• 金额: $ 7.55万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-04-01 至 2013-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8369382
• 关键词: 5' Untranslated Regions; Apoptosis; Area; Binding; Cancer cell line; Cell Cycle Arrest; Cell Line; Cells; Cellular Stress; Cues; DNA Damage; DNA Sequence; Development; Event; Exhibits; Exposure to; Gene Mutation; Gene Targeting; Genes; Genetic; Genetic Transcription; Goals; Human; Internal Ribosome Entry Site; Lead; Link; MDM2 gene; MDM2 gene; Maintenance; Malignant - descriptor; Malignant Neoplasms; Mediating; Messenger RNA; Mutate; Pathogenesis; Play; Post-Translational Protein Processing; Protein p53; Proteins; Regulation; Research; Role; Signal Transduction; TP53 gene; Testing; Trans-Activators; Transcriptional Activation; Translational Regulation; Translations; Tumor Suppressor Proteins; Up-Regulation; anticancer research; cancer cell; carcinogenesis; cell injury; cell transformation; chemical carcinogen; chemotherapeutic agent; cytotoxic; environmental agent; genetic regulatory protein; insight; neoplastic cell; novel; p53-binding protein; public health relevance; research and development; response; tumorigenesis; tumorigenic; ultraviolet irradiation