Defective p53 synthesis following DNA damage and cancer development
Defective p53 synthesis following DNA damage and cancer development
批准号:
8369382
负责人:
Da-Qing Yang
金额:
$7.55万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2010
资助国家:
美国
项目状态:
已结题
起止时间:
2010-04-01 至 2013-03-31
关键词:
5&apos Untranslated RegionsApoptosisAreaBindingCancer cell lineCell Cycle ArrestCell LineCellsCellular StressCuesDNA DamageDNA SequenceDevelopmentEventExhibitsExposure toGene MutationGene TargetingGenesGeneticGenetic TranscriptionGoalsHumanInternal Ribosome Entry SiteLeadLinkMDM2 geneMDM2 geneMaintenanceMalignant - descriptorMalignant NeoplasmsMediatingMessenger RNAMutatePathogenesisPlayPost-Translational Protein ProcessingProtein p53ProteinsRegulationResearchRoleSignal TransductionTP53 geneTestingTrans-ActivatorsTranscriptional ActivationTranslational RegulationTranslationsTumor Suppressor ProteinsUp-Regulationanticancer researchcancer cellcarcinogenesiscell injurycell transformationchemical carcinogenchemotherapeutic agentcytotoxicenvironmental agentgenetic regulatory proteininsightneoplastic cellnovelp53-binding proteinpublic health relevanceresearch and developmentresponsetumorigenesistumorigenicultraviolet irradiation
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海外基金