Enhanced Parallel MRI Data Acquisition

增强型并行 MRI 数据采集

• 批准号: 8286360
• 负责人: GARY P ZIENTARA
• 金额: $ 17.84万
• 依托单位: BRIGHAM AND WOMEN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-05-01 至 2013-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8286360
• 关键词: Address; Adult; Communication; Computer software; Computers; Coupled; Detection; Development; Diagnosis; Frequencies; Funding; Gel; Goals; Hospitals; Human; Image; Institutional Review Boards; Logistics; Magnetic Resonance Imaging; Methods; Modality; Needles; Operative Surgical Procedures; Physicians; Physics; Procedures; Process; Prostate; Public Health; Publishing; RF coil; Research; Research Personnel; Resolution; Robotics; Sampling; Scanning; Signal Transduction; System; Techniques; Technology; Testing; Three-Dimensional Imaging; Translating; Translations; Work; data acquisition; design; image guided therapy; imaging modality; improved; in vivo; neurosurgery; new technology; prevent; programs; research study; software systems; tool; volunteer

MRI technology for MR-guided therapies and surgeries in the AMIGO suite is unique. While the therapies and surgeries have the need for fast dynamic MRI as in past interventional MRI applications, the MR technology in the AMIGO suite also can benefit from information coming from other imaging modalities. Due to the number of high technology tools readily available to the interventionalist during procedures in the AMIGO suite, a premium is placed on designing the suite's tools' combined capabilities while preventing the technical aspects of use from becoming overwhelming to the interventionalist during a procedure. There must be information integration and ease of use without information overload to fully take advantage of the AMIGO suite. For this reason we propose an implementation-focused project. This project's dynamic MRI research is directed specifically at MRI needs posed by the unique aspects of the AMIGO suite. The project's main objective is to translate the latest 3D dynamic imaging technical advances - specifically published (previously characterized) techniques in Parallel MRI and reduced field-of-view methods - into practical functions on the 3T 16-channel MRI scanner that will be part of our AMIGO suite. The main objective will be accomplished taking advantage of available information from other imaging modalities, and implementing the functionality to address the AMIGO-specific features mentioned above. The imaging technical goal of this research is for high resolution, sub-second 3D imaging individually tailored for the applications of: MR-guided neurosurgery, prostate therapy, and robotic needle / probe placement. The implementations will be tested and evaluated by performing experiments with gel phantoms healthy adult volunteers and in vivo, working with Project 1, while immediate translation into IRB-certified human tests is possible under other funding and a currently active IRB. A major portion of the advanced technology that we will implement will contribute to forming a fully Broadband MRI (BbMRI) scanner in the AMIGO suite. BbMRI refers to a fully integrated scanner hardware and software system for fast, continuous 3D dynamic MR data acquisition in which each system component transmits or receives a broad band of spatial frequency information. This research is relevant to the public health in that it aims to implement improved dynamic imaging methods for continuous 'tv-like1 imaging, using the most advanced physics and computer technology. The Project aims to bring the new methods directly into the hospital so they are available to those in need. The research also aims to make this new technology easily usable for the physicians so they can better excel in their tasks of detection and diagnosis.

AMIGO套件中用于MR引导治疗和手术的MRI技术是独一无二的。虽然这些疗法 并且外科手术需要快速动态MRI，如在过去的介入MRI应用中， AMIGO套件中的技术也可以从来自其他成像模式的信息中受益。由于 高科技工具的数量在手术过程中随时可供介入医生使用， AMIGO套件，一个溢价是放在设计套件的工具的组合功能，同时防止 在手术过程中，使用的技术方面对介入医生来说变得难以承受。那里 必须是信息集成和易用性，没有信息过载，以充分利用 AMIGO套房为此，我们提出了一个以实施为重点的项目。这个项目的动态磁共振成像 研究是专门针对由AMIGO套件的独特方面提出的MRI需求。该项目的 主要目标是翻译最新的3D动态成像技术进展-特别是出版 并行MRI中的（先前表征的）技术和缩小视野方法-变为实用 功能的3 T 16通道MRI扫描仪，将是我们的AMIGO套件的一部分。主要目标是 利用来自其他成像模态的可用信息，并实现 这是一个新的功能，以解决上述AMIGO特有的功能。这项成像技术的目标是 研究旨在针对以下应用单独定制的高分辨率、亚秒级3D成像：MR引导 神经外科、前列腺治疗和机器人针/探针放置。将测试这些实现 并通过用凝胶体模健康成年志愿者和体内进行实验进行评价， 与项目1，而立即转化为IRB认证的人体测试是可能的其他资金， 目前活跃的IRB。我们将实施的先进技术的主要部分将有助于 在AMIGO套件中形成全宽带MRI（BbMRI）扫描仪。BbMRI是指完全集成的 用于快速、连续3D动态MR数据采集的扫描仪硬件和软件系统，其中每个 系统组件发送或接收宽频带的空间频率信息。本研究是 与公共健康相关，因为其旨在实施改进的动态成像方法，以用于连续成像。 “电视般的成像，使用最先进的物理学和计算机技术。该项目旨在将 新方法直接进入医院，以便有需要的人可以使用。该研究还旨在 使这项新技术易于为医生使用，使他们能够更好地在他们的检测任务中脱颖而出 与诊断