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Administrative and Clinical Support

行政和临床支持

基本信息

批准号：
8249894
负责人：
KENNETH C. ANDERSON
金额：
$ 31.6万
依托单位：
DANA-FARBER CANCER INST
依托单位国家：
美国
项目类别：
财政年份：
2011
资助国家：
美国
起止时间：
2011-04-01 至 2015-03-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8249894
关键词：
Administrative Coordination Administrator Adoptive Transfer Advisory Committees Animal Model Antigen-Presenting Cells Antigens Autologous Cell Communication Clinical Clinical Nursing Research Clinical Research Clinical Trials Clinical Trials Design Communication Disease Drug resistance Evaluation Funding Goals Grant Immune Immunity Immunologics Immunosuppression In Vitro Innovative Therapy Joints Laboratory Finding Laboratory Study Lead Mediating Monoclonal gammopathy of uncertain significance Multiple Myeloma Outcome Patients Phase Publications Research Infrastructure Research Project Grants Residual Neoplasm Resources Role Sampling Signal Transduction T cell response T-Lymphocyte Therapeutic Translations Transplantation Vaccination base bench to bedside cell growth data exchange improved member neoplastic cell novel novel therapeutic intervention preclinical study programs response stem trafficking tumor

项目摘要

Core A will oversee the administrative coordination of the various clinical and laboratory studies outlined in this Program Project. It will integrate scientific and clinical efforts within and between Projects, and assure the translation of laboratory findings to the bedside; and conversely, the initiation of laboratory studies stemming from clinical observations. During the prior funding period, the infrastructure has been created to have seemless communication and exchange of data between Projects, facilitating collaborative preclinical studies and clinical trials. Multiple joint publications, completed and ongoing clinical trials, and the translation of several novel targeted therapies from bench to bedside confirm the communication and integration of our efforts. This Core will continue to facilitate exchange of information among the Program members, as well as the internal and external advisory committees. It will provide clinical research nursing support for the proposed clinical trials. In addition, as in the previous funding period, a clinical study coordinator will assure appropriate sample acquisition and trafficking. The grants administrator will allocate resources in a timely and integrated fashion to facilitate successful completion of the proposed studies. Core A will provide these functions: 1. To integrate scientific and clinical efforts within and between Projects 2. To assure translation of laboratory findings to the bedside; and conversely, the initiation of laboratory studies stemming from clinical observations. 3. To provide administrative support for the Projects.

核心A将监督本计划项目中概述的各种临床和实验室研究的行政协调。它将整合项目内部和项目之间的科学和临床工作，并确保将实验室结果转化为临床结果;相反，启动源于临床观察的实验室研究。在上一个资助期间，已经创建了基础设施，以便在项目之间进行无障碍通信和数据交换，促进合作的临床前研究和临床试验。多个联合出版物，已完成和正在进行的临床试验，以及从实验室到床边的几种新型靶向疗法的翻译证实了我们努力的沟通和整合。该核心将继续促进方案成员以及内部和外部咨询委员会之间的信息交流。将为拟开展的临床试验提供临床研究护理支持。此外，与上一个资助期一样，临床研究协调员将确保适当的样本采集和运输。赠款管理人将及时和综合地分配资源，以促进成功完成拟议的研究。核心A将提供这些功能： 1.在项目内部和项目之间整合科学和临床工作 2.确保将实验室检查结果转化为临床结果;相反，启动源于临床观察的实验室研究。 3.为项目提供行政支持。