Improving anti-cancer therapy by stromal targeting and remodelling

我们已经开发出一种新药，可以与异常的癌症血管结合。一旦结合，癌症血管的形状和强度就会恢复，它们会变得更加紧密。我们的研究现在将测试将这种新药与目前的标准护理疗法(如化疗和免疫疗法)相结合，是否会改进细胞毒药物，并使免疫系统更好地与癌症作斗争。我们还预计，血管的收紧将阻止癌细胞在全身扩散。

We have developed a new drug which binds to abnormal cancer blood vessels. Upon binding, shape and tone of cancer vessels are restored and they become tighter. Our research will now test whether combining this new drug with current standard-of-care therapies such as chemo- and immunotherapy, will improve cytotoxic drugs and also make the immune system work better to fight the cancer. We also expect that tightening of blood vessels will stop cancer cells from spreading throughout the body.