Targeting inflammation-associated macrophages for imaging and therapy

针对炎症相关巨噬细胞进行成像和治疗

• 批准号: nhmrc : 1046507
• 负责人: A/Pr Juliana Hamzah
• 金额: $ 27.69万
• 依托单位: The University of Western Australia
• 依托单位国家: 澳大利亚
• 项目类别: Career Development Fellowships
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/targeting-inflammation-associated-imaging-therapy/111847
• 关键词: Targeting; inflammation; associated; macrophages; imaging

Cancer and cardiovascular disease are the most common causes of morbidity and mortality worldwide. The development of effective therapies remains a major challenge and is often associated with severe side-effects. I recently developed novel targeting reagents to effectively deliver therapeutics and diagnostic agents deep inside diseased tissues, such as tumours and atherosclerotic plaques. My research will further explore their therapeutic and imaging applications in cancer and atherosclerosis.

癌症和心血管疾病是全世界发病率和死亡率最常见的原因。开发有效的治疗方法仍然是一个重大挑战，并且通常与严重的副作用有关。我最近开发了新的靶向试剂，以有效地将治疗剂和诊断剂深入病变组织，如肿瘤和动脉粥样硬化斑块。我的研究将进一步探索它们在癌症和动脉粥样硬化中的治疗和成像应用。