OPTIMIZING THE DELIVERY OF GENE THERAPY FOR PARKINSON?S DISEASE

优化帕金森病基因治疗的实施

• 批准号: 8358240
• 负责人: MARINA EMBORG
• 金额: $ 1.57万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-05-01 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8358240
• 关键词: Disease; Funding; Grant; Image; Infusion procedures; Magnetic Resonance Imaging; Methods; Monitor; National Center for Research Resources; Parkinson Disease; Primates; Principal Investigator; Research; Research Infrastructure; Resources; Source; System; Time; United States National Institutes of Health; Viral Vector; Wisconsin; cost; gene therapy; improved

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Objective: To improve the methods of intracerebral delivery of trophic factor gene therapy by comparing different viral vectors systems and using real time MRI imaging for intracerebral navigation and monitoring of infusions. This ICTR Type I project recently began and progress is forthcoming.

该副本是利用资源的众多研究子项目之一 由NIH/NCRR资助的中心赠款提供。对该子弹的主要支持 而且，副投影的主要研究员可能是其他来源提供的 包括其他NIH来源。 列出的总费用可能 代表subproject使用的中心基础架构的估计量， NCRR赠款不直接向子弹或副本人员提供的直接资金。 目的：通过比较不同的病毒载体系统，并使用实时MRI成像进行脑内导航和监测输注，以改善营养因子基因治疗的脑内递送方法。 这个ICTR类型的I项目最近开始了，进展即将到来。