STEM CELL & REGENERATIVE MEDICINE CENTER NONHUMAN PRIMATES CORE

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的， 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 目的：验证股骨柄植入的可行性、有效性及可能的副作用 在非人灵长类动物的翻译前研究中使用基于细胞的疗法。 进展： 这项服务开始于2007年7月，随着新的威斯康星大学麦迪逊分校干细胞和 再生医学中心。开发细胞替代疗法的项目可能 要求研究人员在体外研究灵长类细胞或将干细胞植入 非人灵长类动物来测试疗效并评估可能的副作用， 进行人体试验在这方面，需要专门知识、实验室设施和 动物是通过非人类灵长类动物服务中心提供的， 威斯康星州国家灵长类动物研究中心。具体服务包括： 适当的猴子和灵长类动物组织的项目，专门的畜牧业， 协助猴子的手术和临床评估等程序， 适当的终末程序和用于分析的组织制备，以及 提供专门工具。 出版物： 没有。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Objective: To test feasibility and efficacy, and assess possible side effects, of stem cell based therapies in pre-translational studies with nonhuman primates. PROGRESS: This service began in July 2007, with the launch of the new UW-Madison Stem Cell & Regenerative Medicine Center. Projects to develop cell replacement therapies may require researchers to study primate cells in vitro or implant stem cells into nonhuman primates to test efficacy and assess possible side effects before proceeding to human trials. In this context, expertise, laboratory facilities and animals are made available through the Nonhuman Primate Services core at the Wisconsin National Primate Research Center. Specific services include the provision of appropriate monkeys and primate tissue for projects, specialized animal husbandry, assistance with procedures such as surgeries and clinical assessments of monkeys, appropriate terminal procedures and preparation of tissues for analysis, and provision of specialized instruments. PUBLICATIONS: None.