Third International Chordoma Research Workshop: Catalyzing New Advances in Chordo

第三届国际脊索瘤研究研讨会：催化脊索瘤新进展

• 批准号: 8245351
• 负责人: Edward Les
• 金额: $ 0.5万
• 依托单位: CHORDOMA FOUNDATION
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-03-18 至 2011-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8245351
• 关键词: Acceleration; Affect; Applications Grants; Area; Basic Science; Biological; Chordoma; Clinic; Clinical; Collaborations; Communities; Country; Development; Diagnosis; Discipline; Disease; Educational workshop; Evaluation; Feedback; Fertilization; Fostering; Foundations; Future; Genomics; Goals; Institution; International; Investigation; Knowledge; Lead; Learning; Malignant Bone Neoplasm; Malignant Neoplasms; Medical; Nature; Orphan; Outcome; Participant; Patient Care; Patients; Physicians; Publishing; Request for Applications; Research; Research Personnel; Resources; Schedule; Science; Scientist; Solutions; Specialist; Strategic Planning; Suggestion; Techniques; Translating; Tuberous sclerosis protein complex; Update; Vertebral column; Woman; clinical care; design; drug development; effective therapy; forging; improved; interest; medical specialties; meetings; multidisciplinary; neglect; posters; public health relevance; research and development; sarcoma; skull base; success; symposium; therapy development; working group

DESCRIPTION (provided by applicant): This grant application requests partial support for the Third International Chordoma Research Workshop (ICRW) which will be coordinated and co-sponsored by the Chordoma Foundation, a 501(c)(3) nonprofit foundation, established in 2007, to rapidly advance chordoma research. This workshop aims to catalyze new advances in chordoma research and treatment development by providing a forum for investigators to exchange new information and ideas, to forge new collaborations, and to collectively plan future research necessary to create effective treatments for chordoma patients. The workshop will be held at the Bethesda North Marriott tentatively scheduled on October 14-16, 2010, for 100 participants. It will include didactic presentations followed by group discussions, a poster presentation, small round-table discussions, and breakout working group sessions. These various sessions are designed to provide opportunities for the exchange of knowledge and ideas, debate, strategic planning, networking and partnership-building. Building on the success of the two previous International Chordoma Research Workshops in 2007 and 2008, this workshop will bring together a diverse array of multidisciplinary specialists including treating physicians; basic science, translational, and clinical researchers interested in chordoma; leaders in the patient community, and experts in related fields, such as genomics and drug development, who possess knowledge, resources, or techniques applicable to advancing chordoma research. Women scientists are well represented and special efforts will be made to involve both scientists and clinicians from underrepresented communities. The workshop will provide a unique opportunity for cross-fertilization of ideas among participants with diverse expertise and will enable investigators to develop partnerships with colleagues from different disciplines, institutions and countries. The overarching theme will be integrating and acting upon the significant amount of new information about chordoma that has been generated since the last ICRW in 2008. During the workshop participants will discuss the latest advances in chordoma research and clinical care, and will identify important questions and areas for further investigation. Treating physicians will discuss issues related to patient care and will share observations from the clinic that will help inform basic research scientists. Special emphasis will be placed on exploring clinical and biological commonalities with related diseases including other sarcomas and Tuberous Sclerosis Complex. In addition, systemic issues affecting the progress of chordoma research and the quality of patient care will be evaluated, barriers will be identified, and solutions will be proposed. These discussions are expected to culminate in the development of concrete research goals, and revision of the Chordoma Research Roadmap developed at the previous two International Chordoma Research Workshops in 2007 and 2008. Ultimately the results of the research catalyzed by this workshop will lead to improved diagnosis and treatment, and better long-term outcomes for patients with chordoma. PUBLIC HEALTH RELEVANCE: Lessons learned from neglected and orphaned cancers such as chordoma, a primary malignancy of the base of skull and spine, are revealing new information that can be translated to more common cancers. The rapid worldwide acceleration of chordoma research at an unprecedented pace since the First International Chordoma Research Workshop (ICRW) in 2007 warrants the need for the Third ICRW in 2010. "The Third International Chordoma Research Workshop: Catalyzing New Advances in Chordoma Research" is scheduled for October 14 - 16, 2010 at the North Bethesda Marriott Hotel & Conference Center in Bethesda MD. One hundred attendees are anticipated. This dynamic workshop convenes leading physicians and research scientists with diverse expertise to share new research results, foster open exchange of information, spark new research questions, and promote international collaborations. The outcome of this workshop will translate to improved treatments for patients with this deadly bone cancer.

描述（由申请人提供）：本资助申请要求对第三届国际合唱研究研讨会（ICRW）的部分支持，该研讨会将由合唱基金会协调和共同赞助，该基金会是一个501（c）（3）非营利基金会，成立于2007年，以迅速推进合唱研究。本次研讨会旨在通过为研究人员提供一个论坛来交流新的信息和想法，建立新的合作，并共同规划为脉络膜患者创造有效治疗所需的未来研究，从而促进脉络膜研究和治疗开发的新进展。研讨会将于2010年10月14日至16日在贝塞斯达北万豪酒店举行，有100名与会者。它将包括教学演示，然后是小组讨论，海报演示，小型圆桌讨论和分组工作组会议。这些不同的会议旨在为交流知识和想法、辩论、战略规划、建立联系和建立伙伴关系提供机会。 在2007年和2008年前两次国际合唱研究研讨会成功的基础上，这次研讨会将汇集各种多学科专家，包括治疗医生;对合唱感兴趣的基础科学，翻译和临床研究人员;患者社区的领导者和相关领域的专家，如基因组学和药物开发，他们拥有知识，资源，或适用于推进合唱研究的技术。女科学家的代表性很强，将作出特别努力，让代表性不足的社区的科学家和临床医生参与进来。讲习班将提供一个独特的机会，使具有不同专门知识的参与者能够相互交流思想，并使调查人员能够与来自不同学科、机构和国家的同事建立伙伴关系。总的主题将是整合自2008年国际妇女研究中心上一次会议以来产生的关于合唱团的大量新信息，并根据这些信息采取行动。在研讨会期间，与会者将讨论在脉络膜研究和临床护理的最新进展，并将确定重要的问题和进一步调查的领域。治疗医生将讨论与患者护理相关的问题，并将分享来自诊所的观察结果，这将有助于告知基础研究科学家。特别强调将放在探索与相关疾病，包括其他肉瘤和恶性硬化症的临床和生物学共性。此外，将评估影响脉络膜研究进展和患者护理质量的系统性问题，确定障碍，并提出解决方案。这些讨论预计将最终在具体的研究目标的发展，并在2007年和2008年前两次国际合唱研究研讨会制定的合唱研究路线图的修订。最终，由这次研讨会催化的研究结果将导致改善诊断和治疗，以及更好的长期结果为患者与脉络膜。 公共卫生相关性：从被忽视和孤立的癌症，如脉络膜癌，颅底和脊柱的原发性恶性肿瘤，吸取的教训，揭示了新的信息，可以转化为更常见的癌症。自2007年第一届国际合唱研究讲习班以来，世界各地的合唱研究以前所未有的速度迅速加速，因此有必要在2010年举办第三届国际合唱研究讲习班。 “第三届国际合唱研究研讨会：催化合唱研究的新进展”定于2010年10月14日至16日在北贝塞斯达万豪酒店及会议中心在贝塞斯达马里兰州。预计将有100名与会者。这个充满活力的研讨会召集了具有不同专业知识的领先医生和研究科学家，分享新的研究成果，促进开放的信息交流，引发新的研究问题，并促进国际合作。这次研讨会的成果将转化为改善这种致命骨癌患者的治疗方法。