Third International Chordoma Research Workshop: Catalyzing New Advances in Chordo

第三届国际脊索瘤研究研讨会：催化脊索瘤新进展

• 批准号: 8008708
• 负责人: Edward Les
• 金额: $ 1.5万
• 依托单位: CHORDOMA FOUNDATION
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-08-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8008708
• 关键词: Acceleration; Affect; Applications Grants; Area; Basic Science; Biological; Chordoma; Clinic; Clinical; Collaborations; Communities; Country; Development; Diagnosis; Discipline; Disease; Educational workshop; Evaluation; Feedback; Fertilization; Fostering; Foundations; Future; Genomics; Goals; Information Resources; Institution; International; Investigation; Knowledge; Lead; Learning; Malignant Bone Neoplasm; Malignant Neoplasms; Medical; Nature; Orphan; Outcome; Participant; Patient Care; Patients; Physicians; Publishing; Request for Applications; Research; Research Personnel; Research Project Grants; Schedule; Science; Scientist; Solutions; Specialist; Strategic Planning; Suggestion; Techniques; Translating; Tuberous sclerosis protein complex; Update; Vertebral column; Woman; clinical care; design; drug development; effective therapy; forging; improved; interest; medical specialties; meetings; multidisciplinary; neglect; posters; public health relevance; sarcoma; skull base; success; symposium; therapy development; working group

DESCRIPTION (provided by applicant): This grant application requests partial support for the Third International Chordoma Research Workshop (ICRW) which will be coordinated and co-sponsored by the Chordoma Foundation, a 501(c)(3) nonprofit foundation, established in 2007, to rapidly advance chordoma research. This workshop aims to catalyze new advances in chordoma research and treatment development by providing a forum for investigators to exchange new information and ideas, to forge new collaborations, and to collectively plan future research necessary to create effective treatments for chordoma patients. The workshop will be held at the Bethesda North Marriott tentatively scheduled on October 14-16, 2010, for 100 participants. It will include didactic presentations followed by group discussions, a poster presentation, small round-table discussions, and breakout working group sessions. These various sessions are designed to provide opportunities for the exchange of knowledge and ideas, debate, strategic planning, networking and partnership-building. Building on the success of the two previous International Chordoma Research Workshops in 2007 and 2008, this workshop will bring together a diverse array of multidisciplinary specialists including treating physicians; basic science, translational, and clinical researchers interested in chordoma; leaders in the patient community, and experts in related fields, such as genomics and drug development, who possess knowledge, resources, or techniques applicable to advancing chordoma research. Women scientists are well represented and special efforts will be made to involve both scientists and clinicians from underrepresented communities. The workshop will provide a unique opportunity for cross-fertilization of ideas among participants with diverse expertise and will enable investigators to develop partnerships with colleagues from different disciplines, institutions and countries. The overarching theme will be integrating and acting upon the significant amount of new information about chordoma that has been generated since the last ICRW in 2008. During the workshop participants will discuss the latest advances in chordoma research and clinical care, and will identify important questions and areas for further investigation. Treating physicians will discuss issues related to patient care and will share observations from the clinic that will help inform basic research scientists. Special emphasis will be placed on exploring clinical and biological commonalities with related diseases including other sarcomas and Tuberous Sclerosis Complex. In addition, systemic issues affecting the progress of chordoma research and the quality of patient care will be evaluated, barriers will be identified, and solutions will be proposed. These discussions are expected to culminate in the development of concrete research goals, and revision of the Chordoma Research Roadmap developed at the previous two International Chordoma Research Workshops in 2007 and 2008. Ultimately the results of the research catalyzed by this workshop will lead to improved diagnosis and treatment, and better long-term outcomes for patients with chordoma. PUBLIC HEALTH RELEVANCE: Lessons learned from neglected and orphaned cancers such as chordoma, a primary malignancy of the base of skull and spine, are revealing new information that can be translated to more common cancers. The rapid worldwide acceleration of chordoma research at an unprecedented pace since the First International Chordoma Research Workshop (ICRW) in 2007 warrants the need for the Third ICRW in 2010. "The Third International Chordoma Research Workshop: Catalyzing New Advances in Chordoma Research" is scheduled for October 14 - 16, 2010 at the North Bethesda Marriott Hotel & Conference Center in Bethesda MD. One hundred attendees are anticipated. This dynamic workshop convenes leading physicians and research scientists with diverse expertise to share new research results, foster open exchange of information, spark new research questions, and promote international collaborations. The outcome of this workshop will translate to improved treatments for patients with this deadly bone cancer.

描述(由申请人提供)：本赠款申请请求为第三届国际脊索瘤研究研讨会(ICRW)提供部分支持，该研讨会将由脊索瘤基金会协调和共同赞助，该基金会是一个成立于2007年的501(C)(3)非营利性基金会，旨在迅速推进脊索瘤研究。这次研讨会旨在通过为研究人员提供一个论坛，交流新的信息和想法，建立新的合作关系，并共同规划为脊索瘤患者创造有效治疗所需的未来研究，从而促进脊索瘤研究和治疗开发方面的新进展。研讨会将于2010年10月14日至16日在北贝塞斯达万豪酒店举行，有100人参加。它将包括说教报告，然后是小组讨论，海报演示，小型圆桌讨论，以及分组工作组会议。这些不同的会议旨在为交流知识和想法、辩论、战略规划、联网和建立伙伴关系提供机会。 在2007年和2008年举办的前两届国际脊索瘤研究研讨会取得成功的基础上，本次研讨会将汇集各式各样的多学科专家，包括治疗医生；对脊索瘤感兴趣的基础科学、翻译和临床研究人员；患者社区的领导者；以及拥有适用于推进脊索瘤研究的知识、资源或技术的相关领域的专家，如基因组学和药物开发。女科学家有很好的代表性，将作出特别努力，让来自代表性不足社区的科学家和临床医生参与进来。讲习班将提供一个独特的机会，让具有不同专门知识的与会者交流思想，并使调查人员能够与来自不同学科、机构和国家的同事发展伙伴关系。最重要的主题将是整合自2008年上一次国际研究报告以来产生的大量有关脊索瘤的新信息并采取行动。在研讨会期间，与会者将讨论脊索瘤研究和临床护理的最新进展，并将确定需要进一步研究的重要问题和领域。治疗医生将讨论与患者护理相关的问题，并将分享诊所的观察结果，这将有助于为基础研究科学家提供信息。将特别重视探索与其他肉瘤和结节性硬化症等相关疾病的临床和生物学共性。此外，还将评估影响脊索瘤研究进展和患者护理质量的系统性问题，确定障碍，并提出解决方案。预计这些讨论将最终制定具体的研究目标，并修订2007年和2008年前两次国际脊索瘤研究讲习班制定的脊索瘤研究路线图。最终，本研讨会推动的研究结果将改善脊索瘤患者的诊断和治疗，并改善患者的长期结果。 公共卫生相关性：从被忽视的和孤儿癌症中吸取的经验教训，如脊索瘤，一种颅底和脊柱底部的主要恶性肿瘤，正在揭示新的信息，这些信息可以转化为更常见的癌症。自2007年第一次国际脊索瘤研究研讨会(ICRW)以来，全球脊索瘤研究以前所未有的速度迅速加速，因此有必要在2010年召开第三次国际脊索瘤研究研讨会。 “第三届国际脊索瘤研究研讨会：推动脊索瘤研究的新进展”定于2010年10月14-16日在马里兰州贝塞斯达的北贝塞斯达万豪酒店和会议中心举行。预计将有100人参加。这个充满活力的研讨会召集了具有不同专业知识的领先医生和研究科学家，以分享新的研究成果，促进开放的信息交流，引发新的研究问题，并促进国际合作。这次研讨会的成果将转化为改善这种致命骨癌患者的治疗方法。