TAS::75 0893::TAS SYNTHESIS AND DISTRIBUTION OF OPIOID AND RELATED PEPTIDES

大约二十年来，国家药物滥用研究所（NIDA）一直在为致力于药物滥用问题的科学研究界提供真正的、标准化的受管制的研究药物和化学品供应。这些药物和化学物质包括大麻和大麻香烟，各种大麻素，已知的致幻剂，海洛因，安非他明，以及许多其他对临床前和临床研究至关重要的药物。目前供研究使用的受管制药物和包括类阿片肽在内的其他化学品的数量大幅增加，原因是多种因素共同作用导致需求不断增加，这些因素包括监管要求的增加往往会阻碍商业化供应，以及药物滥用领域的研究工作迅速扩大。

For about two decades, the National Institute on Drug Abuse (NIDA) has been providing the scientific research community working on problems of drug abuse with authentic, standardized supplies of controlled research drugs and chemicals. Such drugs and chemicals include marijuana and marijuana cigarettes, various cannabinoids, known hallucinogens, heroin, amphetamines, and many others that are essential for pre-clinicla and clinical research. The number of controlled drug substances and other chemicals including opioid peptides that are currently supplied for research has grown significantly because of increasing demand due to a combination of factors including increased regulatory requirements that tend to discourage commercial availability and rapidly expanding research efforts in the area of drug abuse. In order to meet demand for authentic peptides, NIDA plans to continue to maintain an inventory of about 53-55 peptides and some of their respective radio labeled peptides (30-35) for use in NIDA supported studies.