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英文摘要
The goal of this program is to support systems biology analyses of innate and/or adaptive immune responses, with a focus on NIAID Category A, B, and C priority pathogens. The analysis will be based on high-throughput screens of existing or novel mouse models for identification of key regulatory immune response genes, supported by detailed genomics, proteomics, computational biology, and bioinformatics approaches to determine the gene products' functions. Human correlation studies will be performed on a subset of the immune regulatory genes identified in the mouse using human cells or tissues.
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Systems Approach to Immunity and Inflammation
  • 批准号:
    10242980
  • 项目类别:
  • 资助金额:
    $47.2万
  • 财政年份:
    2020
  • 负责人:
    Richard J Ulevitch
  • 依托单位:
Systems Approach to Immunity and Inflammation
  • 批准号:
    10159667
  • 项目类别:
  • 资助金额:
    $36.66万
  • 财政年份:
    2020
  • 负责人:
    Richard J Ulevitch
  • 依托单位:
Systems Approach to Immunity and Inflammation
  • 批准号:
    10291571
  • 项目类别:
  • 资助金额:
    $188.73万
  • 财政年份:
    2020
  • 负责人:
    Richard J Ulevitch
  • 依托单位:
Human Correlation Core
  • 批准号:
    10181123
  • 项目类别:
  • 资助金额:
    $15.14万
  • 财政年份:
    2020
  • 负责人:
    Richard J Ulevitch
  • 依托单位:
海外基金