H3ABioNet: a sustainable African Bioinformatics Network for H3Africa

H3ABioNet：H3Africa 的可持续非洲生物信息学网络

• 批准号: 8540500
• 负责人: Nicola Mulder
• 金额: $ 10.5万
• 依托单位: UNIVERSITY OF CAPE TOWN
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-08-15 至 2013-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8540500
• 关键词: Africa; African; Bioinformatics; Biological; Biology; Biomedical Research; Communication; Data; Data Storage and Retrieval; Databases; Deposition; Development; Ensure; Ethics; Genetic; Genetic Medicine; Genomics; Goals; Health; Health Sciences; Healthcare; Heredity; Human; Human Resources; Intellectual Property; Medicine; Molecular; Molecular Biology; Outcome; Output; Participant; Patients; Population; Research; Research Infrastructure; Research Personnel; Research Project Grants; Resources; Scientist; Secure; Solutions; Structure; Students; Systems Biology; Training; Training Support; Translations; analytical tool; data management; empowered; improved; member; next generation; outreach; research and development; skills; socioeconomics; tool

DESCRIPTION (provided by applicant): H3ABioNet aims to create a sustainable African Bioinformatics Network to support H3Africa researchers through the development of bioinformatics capacity on the continent. Specifically, it aims to: 1) engage with the H3Africa Consortium, providing a framework for integration and communication amongst its members to ensure progress towards the common goal of full exploitation of our genomic and environmental resources for translation into improved health in Africa; 2) develop a core bioinformatics infrastructure (hardware and human resources) to aid research in genomic medicine, high throughput biology, systems biology, genetics, and medicine, for the study of human heredity and health; S) develop tools and bioinformatics solutions appropriate for exploitation and interpretation of biological information in Africa, and make these more accessible to H3Africa researchers; 4) develop research partnerships and promote interaction between bioinformaticians, clinicians, molecular geneticists and ethics researchers to ensure integrative research into health issues in Africa; 5) develop the bioinformatics capacity of people in Africa t empower them to perform cutting edge research, and to ensure retention of bioinformatics skills on the continent; 6) facilitate secure, high-fidelity storage and management of data generated within the H3Africa framework and their deposition in public databases, so that maximum value can be derived from these data; and 7) ensure that the increasing amount of information from genomic analyses and high-throughput molecular biology is accessible to all H3Africa researchers, to promote health research, scientific progress and global competitiveness in Africa. These aims will be achieved through four major activities: user support, training and capacity development, research and tools, and outreach and communication. These activities will result in a bioinformatics support structure, continuous specialized training for bioinformaticians and researchers, development and accessibility of new tools appropriate for the African setting, and a framework for communication flow within the H3Africa Consortium. Through the pooling of existing expertise and training of the next generation of researchers, we will build critical mass in bioinformatics for H3Africa.

描述（申请人提供）：H3ABIONET旨在建立一个可持续的非洲生物信息学网络，以通过开发非洲大陆的生物信息学能力来支持H3AFRICA研究人员。具体而言，它的目的是：1）与H3africa联盟互动，为成员之间的融合和沟通提供了一个框架，以确保朝着完全开发我们的基因组和环境资源的共同目标，以将非洲改善的健康转化为改善健康； 2）开发一种核心生物信息学基础设施（硬件和人力资源），以帮助研究人类遗传和健康的基因组医学，高通量生物学，系统生物学，遗传学和医学的研究； s）开发适用于非洲生物信息的工具和生物信息学解决方案，并使H3africa研究人员更容易获得这些解决方案； 4）建立研究伙伴关系并促进生物信息学家，临床医生，分子遗传学家和道德研究人员之间的互动，以确保非洲健康问题的融合研究； 5）发展非洲人民的生物信息学能力，使他们有能力进行尖端研究，并确保在非洲大陆上保留生物信息学技能； 6）促进H3Africa框架中生成的数据及其在公共数据库中产生的数据的安全，高保真存储和管理，以便可以从这些数据中得出最大值； 7）确保所有H3AFRICA研究人员都可以访问基因组分析和高通量分子生物学的信息量增加，以促进非洲的健康研究，科学进步和全球竞争力。这些目标将通过四个主要活动来实现：用户支持，培训和能力开发，研究和工具以及宣传与沟通。这些活动将导致生物信息学支持结构，为生物信息学家和研究人员进行连续的专业培训，适合非洲环境的新工具的开发和可访问性，以及在H3africa联盟内提供通信流的框架。通过汇总下一代研究人员的现有专业知识和培训，我们将在H3africa的生物信息学方面建立关键的质量。