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ROLE OF IMMUNE ACTIVATION IN SIV PATHOGENESIS

ROLE OF IMMUNE ACTIVATION IN SIV PATHOGENESIS
免疫激活在 SIV 发病机制中的作用
批准号：
8357276
负责人：
JOSEPH M MCCUNE
金额：
$19.14万
依托单位：
UNIVERSITY OF CALIFORNIA AT DAVIS
依托单位国家：
美国
项目类别：
财政年份：
2011
资助国家：
美国
项目状态：
已结题
起止时间：
2011-05-01 至 2012-04-30
来源：
https://reporter.nih.gov/project-details/8357276
关键词：
CaliforniaFrequenciesFundingGrantNational Center for Research ResourcesPathogenesisPrimatesPrincipal InvestigatorRegulatory T-LymphocyteResearchResearch InfrastructureResourcesRoleSIVSourceUnited States National Institutes of Healthage relatedcostimmune activationin vivo

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中文摘要
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英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The objective of this study are to identify 1) the role of regulatory T cells in SIV pathogenesis, 2) In vivo expansion of regulatory T cells and its effect on SIV pathogenesis, and 3) Age-dependent differences in Treg frequencies and function.
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