STRUCTURAL BASIS OF AMBLYOPIA & STRABISMUS

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的， 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 本项目的目的是建立一个人类斜视的动物模型。 为了提供人类外斜视的动物模型，在幼年猕猴的内直肌中进行游离腱切断术。 当动物年龄足够大时，用视频眼动仪记录眼动，我们测量了它们的引导，眼对准，跟随，平滑追踪，固定偏好和凝视稳定性。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The objective of this project is to develop an animal model of human strabismus. To provide an animal model of human exotropia, a free tenotomy was preformed in infant macaques of the medial recti. When the animals were old enough to record eye movements with video eye trackers, we measured their ductions, ocular alignment, comitance, smooth pursuit, fixation preference, and gaze stability.