COBRE: RIH: CORE C: MOLECULAR PATHOLOGY, TRANSGENIC RAT, ANIMAL MODEL OF CANCER

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的， 包括其它NIH来源。 为子项目列出的总成本可能 代表子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 分子病理学核心为病理学系工作人员、COBRE癌症研究发展中心成员和学术界的研究工作提供最先进的仪器和支持人员。 收费服务包括激光捕获显微切割、定量实时PCR、组织微阵列生产、组织库、自动免疫组织化学染色、数据和图像分析。我们的1300平方米英尺机构位于罗得岛医院的奥尔德里奇大楼。 超过32个研究小组使用了我们的服务和设施。 可用性：研究者需要填写一份详细的组织申请表，可通过我们的网站www.lifespan.org/rih/services/cobre获得。 需要IRB项目批准。 费用：请参阅网站费用清单：www.lifespan.org/rih/services/cobre 生物分析仪QC 主要装备 Arturus Autopix激光捕获显微切割系统 Ventana发现系统 Agilent Bioanalyzer Stratagene多重PCR系统 显微镜成像系统 Leica低温恒温器 组织芯片 Revco冷冻机（2） 切片机

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The Molecular Pathology Core provides state-of-the-art instrumentation and support personnel for the research efforts of the Department of Pathology staff, members of the COBRE Center for Cancer Research Development, and academic community. Fee-based services include Laser Capture Microdissection, Quantitative Real-Time PCR, Tissue Microarray production, tissue banking, automated immunohistochemical staining, data and image analysis. Our 1300 sq. ft. facility is located in the Aldrich Building at Rhode Island Hospital. Over 32 research groups have made use of our services and facilities. Availability: Investigators are required to complete a detailed tissue request form obtainable through our website at:www.lifespan.org/rih/services/cobre. IRB project approval is required. Cost: Refer to website for fee list: www.lifespan.org/rih/services/cobre BioAnalyzer QC Major Equipment Arturus Autopix Laser Capture Microdissection System Ventana Discovery System Agilent Bioanalyzer Stratagene Multiplex PCR System Microscope Imaging System Leica Cryostat Tissue Microarrayer Revco Freezers (2) Microtome