YOGA LIFESTYLE INTERVENTION REDUCES BLOOD PRESSURE IN HIV-INFECTED ADULTS

瑜伽生活方式干预可降低感染艾滋病毒的成年人的血压

• 批准号: 8361436
• 负责人: KEVIN E YARASHESKI
• 金额: $ 1.47万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8361436
• 关键词: Adult; Blood Pressure; Body Composition; CD4 Positive T Lymphocytes; Cardiovascular Diseases; Cell Count; Control Groups; Equipment and supply inventories; Fasting; Funding; Grant; HIV; HIV Infections; Insulin; Life; Lipids; Lipoproteins; Mass Spectrum Analysis; Measures; Medical; Monitor; National Center for Research Resources; OGTT; Outcome Study; Plasma; Principal Investigator; Quality of life; RNA; Randomized Controlled Trials; Relative (related person); Research; Research Infrastructure; Resources; Rest; Risk; Risk Factors; Serum; Source; United States National Institutes of Health; Yoga; biomedical resource; cardiovascular disorder risk; cost; effective intervention; health related quality of life; immunological status; improved; lifestyle intervention; prospective; standard of care

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. OBJECTIVE: People living with HIV infection are at increased risk for developing cardiovascular disease (CVD). Safe and effective interventions for lowering CVD risk in HIV infection are high priorities. We conducted a prospective, randomized, controlled study to evaluate whether a yoga lifestyle intervention improves CVD risk factors, virological or immunological status, or quality of life (QOL) in HIV-infected adults relative to standard of care treatment in a matched control group. METHODS: Sixty HIV-infected adults with mild-moderate CVD risk were assigned to 20 weeks of supervised yoga practice or standard of care treatment. Baseline and week 20 measures were: 2-h oral glucose tolerance test with insulin monitoring, body composition, fasting serum lipid/lipoprotein profile, resting blood pressures, CD4 T-cell count and plasma HIV RNA, and the Medical Outcomes Study Short Form (SF)-36 health-related QOL inventory.

该副本是利用资源的众多研究子项目之一 由NIH/NCRR资助的中心赠款提供。对该子弹的主要支持 而且，副投影的主要研究员可能是其他来源提供的 包括其他NIH来源。 列出的总费用可能 代表subproject使用的中心基础架构的估计量， NCRR赠款不直接向子弹或副本人员提供的直接资金。 目的：感染HIV感染的人患心血管疾病（CVD）的风险增加。降低艾滋病毒感染中CVD风险的安全有效干预措施是很高的优先事项。我们进行了一项前瞻性，随机，对照的研究，以评估瑜伽生活方式干预是否改善了HIV感染的成年人在匹配的对照组中相对于护理标准的CVD危险因素，病毒学或免疫学状况或生活质量（QOL）。 方法：将60名患有轻度中度CVD风险的HIV感染的成年人分配到20周的监督瑜伽练习或护理标准治疗。基线和第20周的措施是：2-H口服葡萄糖耐受性测试，包括胰岛素监测，身体成分，空腹血清脂质/脂蛋白谱，静止的血压，CD4 T细胞计数和血浆HIV RNA以及医疗结果研究短形式（SF形式）-36 Health shealth shealth shealth calced qul calced qul calced qul cop intectory。