DIGITAL DATA ACQUISITION SYSTEM

数字数据采集系统

• 批准号: 8361736
• 负责人: MARK A NAIVAR
• 金额: $ 6.71万
• 依托单位: LOS ALAMOS NAT SECTY-LOS ALAMOS NAT LAB
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-01 至 2013-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8361736
• 关键词: 6 year old; Complex; Computer software; Data; Development; Educational process of instructing; Flow Cytometry; Freezing; Funding; Generations; Grant; Kinetics; Lasers; Manufacturer Name; National Center for Research Resources; Operating System; Phase; Physiologic pulse; Principal Investigator; Research; Research Infrastructure; Resources; Running; Signal Transduction; Sorting - Cell Movement; Source; System; Technology; United States National Institutes of Health; analog; computerized data processing; cost; data acquisition; design; detector; digital; experience; flexibility; instrumentation; operation; prototype

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The DiDAC system is now in routine use on four LANL flow cytometers (two phase sensitive flow cytometers, the three-laser system and the rapid mix kinetics cytometer) as well as on the demonstration flow cytometer used to teach a lab on instrumentation principles during the Annual Course in flow cytometry taught in part by the NFCR staff. All the DiDAC systems are running on the Intel platform under the LINUX 6.1 operating system. This system has revolutionary capabilities for very fast and sophisticated control of the operation of all of our cytometers, as well as four-way sorting and waveform recording of the raw data pulses. The design of DiDAC I has been frozen and design of a new generation data acquisition system has begun. DiDAC I uses technologies that are ~6 years old resulting in physically complex modules. One objection of commercial flow cytometer manufacturers to DiDAC I has been that each detector requires an expensive, large format board. Drawing on the experience gained in the DiDAC I development, design of a second-generation system is well underway. The prototype circuit boards will be fabricated by the end of the Resource year. DiDAC II is built around a commercial digital signal processor board that has a stackable bus format. The NFCR designed boards that contain the analog to digital converters and associated circuitry will plug directly into the stack. Boards for four detectors will fit in a 4 x 6 x 6 inch volume. Use of a programmable DSP processor enables a high degree of flexibility in signal processing via software that is not available in DiDAC I.

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的， 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 DiDAC系统目前已在四台LANL流式细胞仪（双相敏感流式细胞仪、三激光系统和快速混合动力学流式细胞仪）以及用于在流式细胞术年度课程期间教授实验室仪器原理的演示流式细胞仪（部分由NFCR工作人员教授）上常规使用。 所有的DiDAC系统都运行在Linux 6.1操作系统下的Intel平台上。 该系统具有革命性的功能，可对所有细胞仪的操作进行非常快速和复杂的控制，以及对原始数据脉冲进行四路分选和波形记录。 DiDAC I的设计已经冻结，新一代数据采集系统的设计已经开始。 DiDAC I使用了大约6年前的技术，导致模块物理复杂。 商用流式细胞仪制造商对DiDAC I的一个反对意见是，每个检测器都需要昂贵的大格式板。 根据在DiDAC I开发中获得的经验，第二代系统的设计正在顺利进行。 原型电路板将在资源年年底前制作完成。 DiDAC II是建立在一个商业数字信号处理器板，具有堆叠总线格式。 NFCR设计的包含模数转换器和相关电路的电路板将直接插入堆栈。 四个探测器的电路板将适合4 x 6 x 6英寸的体积。 使用可编程DSP处理器，可通过软件实现信号处理的高度灵活性，这在DiDAC I中是不可用的。