NEUROANATOMICAL CORRELATES OF READING DEVELOPMENT IN ADOLESCENTS WITH DYSLEXIA

这个子项目是利用资源的许多研究子项目之一。 由NIH/NCRR资助的中心拨款提供。对子项目的主要支持 子项目的首席调查员可能是由其他来源提供的， 包括美国国立卫生研究院的其他来源。为子项目列出的总成本可能 表示该子项目使用的中心基础设施的估计数量， 不是由NCRR赠款提供给次级项目或次级项目工作人员的直接资金。 导言： 阅读障碍是一种发育性疾病，影响多达17%的儿童(Shaywitz，1994)。在研究 阅读障碍的神经生物学，基于体素的形态计量学(VBM)研究显示，在阅读障碍患者脑灰质密度和体积减少 阅读障碍读者与正常读者的左侧顶颞区和左侧枕颞区的比较(Brown et 等人，2001年；M.A.Eckert等人，2005年；Silani等人，2005年)。 具体目标： 使用VBM，这项纵向研究将通过检查阅读的结构关联来扩展先前的研究 青少年阅读困难症读者的发展。 要了解卢卡斯中心正在进行的其他项目，请访问http://rsl.stanford.edu/(卢卡斯年度报告和 ISMRM 2011年摘要) 。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Introduction: Dyslexia is a developmental condition that affects much as 17% of children (Shaywitz, 1994). In examining the neurobiology of dyslexia, voxel-based morphometry (VBM) studies have shown reduced gray matter density and volume in the left parieto-temporal and left occipito-temporal regions of dyslexic readers when compared to normal readers (Brown et al., 2001; M. A. Eckert et al., 2005; Silani et al., 2005). Specific Aims: Using VBM, this longitudinal study will extend upon previous studies by examining the structural correlates of reading development in adolescent dyslexic readers. To read about other projects ongoing at the Lucas Center, please visit http://rsl.stanford.edu/ (Lucas Annual Report and ISMRM 2011 Abstracts) .