RFOV DW/ZONAL OBLIQUE MULTISLICE (ZOOM) COMBINED/READOUT-SEGMENTED (RS)-EPI

RFOV DW/区域斜多切片（变焦）组合/读出分段 (RS)-EPI

• 批准号: 8362958
• 负责人: SAMANTHA HOLDSWORTH
• 金额: $ 1.95万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-01 至 2012-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8362958
• 关键词: Air; Brain region; Diffusion weighted imaging; Echo-Planar Imaging; Funding; Grant; Imaging Techniques; Magnetic Resonance; Methods; National Center for Research Resources; Phase; Physiologic pulse; Principal Investigator; Research; Research Infrastructure; Resources; Series; Source; Spinal Cord; Technology; Tissues; Training; United States National Institutes of Health; cost

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Diffusion-weighted imaging (DWI) using echo-planar imaging (EPI) has been limited by geometric distortion and blurring, particularly in regions with large off-resonance effects such as in the spinal-cord and in regions of the brain residing near tissue/air interfaces. Geometric distortion in EPI is proportional to the FOV in the phase encoding direction (FOVpe), as well as the echo-spacing between adjacent echoes in the EPI train (Tro). To reduce FOVpe and avoid aliasing, here we use the zonal oblique multislice EPI (ZOOM-EPI) technique, which uses a tilted refocusing pulse. To reduce distortion further, Tro can be reduced by covering k-space with a series of consecutive segments or 'blinds', known as RS-EPI. Here we implemented the ZOOM pulse together with the RS-EPI trajectory (ZOOM-RS-EPI) to get the benefits of both methods for reducing distortion.

该子项目是利用资源的众多研究子项目之一 由 NIH/NCRR 资助的中心拨款提供。子项目的主要支持 并且子项目的主要研究者可能是由其他来源提供的， 包括其他 NIH 来源。 子项目可能列出的总成本 代表子项目使用的中心基础设施的估计数量， NCRR 赠款不直接向子项目或子项目工作人员提供资金。 使用平面回波成像 (EPI) 的扩散加权成像 (DWI) 受到几何失真和模糊的限制， 特别是在具有较大偏共振效应的区域，例如脊髓和位于附近的大脑区域 组织/空气界面。 EPI 中的几何畸变也与相位编码方向 (FOVpe) 上的 FOV 成正比 作为 EPI 序列 (Tro) 中相邻回波之间的回波间距。为了减少 FOVpe 并避免混叠，这里我们使用 带状倾斜多层 EPI (ZOOM-EPI) 技术，使用倾斜重聚焦脉冲。为了进一步减少失真，Tro 可以通过用一系列连续的段或“盲区”覆盖 k 空间来减少，称为 RS-EPI。在这里我们 将 ZOOM 脉冲与 RS-EPI 轨迹 (ZOOM-RS-EPI) 一起实施，以获得两种方法的优点 减少失真。