NON-CONTRAST BREATH-HELD RENAL MR ANGIOGRAPHY

这个子项目是利用资源的许多研究子项目之一。 由NIH/NCRR资助的中心拨款提供。对子项目的主要支持 子项目的首席调查员可能是由其他来源提供的， 包括美国国立卫生研究院的其他来源。为子项目列出的总成本可能 表示该子项目使用的中心基础设施的估计数量， 不是由NCRR赠款提供给次级项目或次级项目工作人员的直接资金。 虽然对比增强磁共振血管成像(CEMRA)被广泛应用于血管病理评估，但最近发生的肾脏病变 对全身纤维化(NSF)的担忧在使用基于Gd的造影剂后激发了人们对 非对比MRA方法。平衡稳态自由进动(b-SSFP)成像[1]已经显示出巨大的前景，因为 它的高信噪比和短扫描时间，已在冠状动脉和肾动脉成像中获得成功。健壮的脂肪抑制 由于B0和B1不均匀，在高场强下仍然具有挑战性。传统的脂肪饱和度会降低 SSFP稳定状态，导致重影伪影。我们提出了吉尼斯(Group-Encoded Non Gate Invertion)算法 稳态非对比度增强)一种新的群编码k空间的平衡SSFP-Dixon 3D技术 屏气非对比磁共振血管成像的分割方案。 要了解卢卡斯中心正在进行的其他项目，请访问http://rsl.stanford.edu/(卢卡斯年度报告和 ISMRM 2011年摘要)

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. While contrast-enhanced MR Angiography (CEMRA) is widely used for evaluation of vascular pathology, recent nephrogenic systemic fibrosis (NSF) concerns following administration of Gadolinium based contrast agents have spurred interest in non-contrast MRA methods. Balanced steady state free precession (b-SSFP) imaging [1] has shown great promise due to its high SNR and short scan times and has been successful in coronary and renal artery imaging. Robust fat suppression remains challenging at high field strengths due to B0 and B1 inhomogeneities. Conventional fat saturation compromises the SSFP steady state, causing ghosting artifacts. We propose GUINNESS (Group-encoded Ungated Inversion Nulling for Non-contrast Enhancement in the Steady State) a balanced SSFP-Dixon 3D technique with a novel group-encoded k-space segmentation scheme for breath-held non-contrast MRA. To read about other projects ongoing at the Lucas Center, please visit http://rsl.stanford.edu/ (Lucas Annual Report and ISMRM 2011 Abstracts)