PARALLEL TRANSMIT ENABLED PULSE SEQUENCE DEVELOPMENT FOR HIGH FIELD MRI

用于高场 MRI 的并行传输脉冲序列开发

• 批准号: 8362945
• 负责人: MANOJ SARANANTHAN
• 金额: $ 1.95万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-01 至 2012-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8362945
• 关键词: Annual Reports; Chemicals; Complex; Development; Discrimination; Frequencies; Funding; Grant; Image; Magnetic Resonance; Magnetic Resonance Imaging; Maps; Morphologic artifacts; National Center for Research Resources; Pattern; Physiologic pulse; Predisposition; Principal Investigator; Radio; Reading; Research; Research Infrastructure; Resolution; Resources; Source; Spectrum Analysis; System; Technology; Time; United States National Institutes of Health; Visit; abstracting; combat; cost; design; improved; interest; radiofrequency

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. High field MRI systems have the potential to enable ultra high spatial resolution imaging, provide enhanced susceptibility contrast and improved chemical species discrimination in spectroscopy. However high field MRI also poses challenges in the form of decreased radio frequency (RF) excitation homogeneity. This manifests as shading artifacts in the images, making quantitative imaging challenging. Recent developments in multi-transmit radiofrequency pulse design offer a possibility of combating this by using multiple parallel transmitters to excite a complex pattern in excitation k-space using RF and gradient pulses in multiple channels that results in a net uniform excitation field across the region of interest. One of the key inputs to such an RF pulse design is the so-called B1 map, a spatial mapping of the excitation field, which is a time consuming step. Accurate but fast B1 mapping is hence key in generating shading-free images at high fields. To read about other projects ongoing at the Lucas Center, please visit http://rsl.stanford.edu/ (Lucas Annual Report and ISMRM 2011 Abstracts)

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