WHITE MATTER ARCHITECTURE FROM DIFFUSION MRI

这个子项目是利用资源的许多研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 子项目的主要研究者可能是由其他来源提供的， 包括其它NIH来源。 为子项目列出的总成本可能 表示子项目使用的中心基础设施的估计数量， NCRR赠款不直接向子项目或子项目工作人员提供资金。 白色建筑核心（WMA）的目标是追求技术 这些进展提高了目前对大脑中白色物质解剖学的理解。 鉴于神经通路的尺寸相对于当前成像而言很小 这些技术对于分析和可视化神经解剖结构至关重要 在正常和疾病状态下。临床目的是分析白色 精神分裂症的物质结构，通过使用扩散张量技术 磁共振成像（DT-MRI）和后处理成像。人们期望 从这些研究中获得的新知识不仅有助于理解 和精神分裂症的治疗，而且还广泛用于其他白色疾病。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The goal of the White Matter Architecture core (WMA) is to pursue technological developments that improve current understanding of white matter anatomy in the brain. Given the small dimension of the neural pathways in relation to current imaging resolution, these technologies are vital to analyzing and visualizing the neural anatomy in normal and diseased states. The clinical objective is to analyze abnormalities in white matter architecture that underlie schizophrenia, by using techniques in diffusion tensor magnetic resonance imaging (DT-MRI) and post-process imaging. The expectation is that new knowledge acquired from these studies not only will benefit the understanding and treatment of schizophrenia, but also a broad range of other white matter diseases.