ATOMIC RESOLUTION STRUCTURE AND FUNCTION OF THE RIBOSOME

核糖体的原子分辨率结构和功能

• 批准号: 8361622
• 负责人: JAMIE HD CATE
• 金额: $ 5.48万
• 依托单位: CORNELL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-01 至 2012-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8361622
• 关键词: Antibiotics; Development; Escherichia coli; Funding; Future; Grant; National Center for Research Resources; Principal Investigator; Recycling; Research; Research Infrastructure; Resolution; Resources; Ribosomes; Source; Structure; Translations; United States National Institutes of Health; cost; structural biology

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. This subproject is aimed at determining the structure of the E. coli 70S ribosome in different steps of translation elongation, termination and ribosome recycling. Atomic-resolution structures of the bacterial ribosome in these various steps of translation will aid in the the future development of antibiotics that target the ribosome.

这个子项目是利用这些资源的众多研究子项目之一