Core B: Research Translation Core

研究翻译核心(RTC)是SBRP必不可少的组成部分。RTC的首要目标是将SBRP的研究成果传达给广泛的利益相关者，包括科学界、监管和公共卫生官员、社区卫生组织和公众。RTC将通过发展与政府机构的伙伴关系、技术转让活动以及向广大利益攸关方传播研究成果来实现这些目标。俄勒冈州立大学的多环芳烃研究中心选择将多环芳烃作为重要的和重新出现的环境化学品加以重点研究，生物医学和非生物医学研究项目将提供重要的数据，通过解决目前与全球相关且尚未得到广泛研究的悬而未决的问题，将使科学界受益。这些研究项目将通过开发和应用最先进的分析方法，解决在确定和衡量环境中多环芳烃和其他新出现的令人关切的化学品方面存在的数据差距。这些研究项目将为表征复杂的多环芳烃混合物及其联合毒理机制提供新的数据。这些项目还将提供有关多环芳烃毒代动力学的重要新数据，包括与生命早期阶段暴露有关的风险。RTC将作为催化剂，将这些研究成果转化为对评估个人和人群健康风险做出有意义贡献的方式。RTC的领导集体拥有毒理学、流行病学、环境卫生、教育推广和公共卫生实践方面的经验。RTC领导人将运用他们的知识和经验，将SBRP研究成果有效地传达给利益相关者，包括公共卫生和监管机构、科学界和高危人群。RTC将在整个项目期间与行政核心和研究项目负责人互动，通过沟通SBRP如何最有效地执行对关键利益攸关方最有用的创新研究，并为其提供服务。此外，RTC将在协调和向NIEHS传达俄勒冈州立大学SBRP的信息方面做出重要贡献。

The Research Translation Core (RTC) is a required and integral component of the SBRP. It is the overarching goal of the RTC to communicate research findings from the SBRP to a broad audience of stakeholders including the scientific community, regulatory and public health officials, community health organizations, and the general public. The RTC will meet these objectives through the development of partnerships with government agencies, technology transfer activities, and the communication of research outcomes to a broad audience of stakeholders. The SBRP at Oregon State University has chosen to focus on PAHs as important and re-emerging environmental chemicals, and the biomedical and non-biomedical research projects will provide important data that will benefit the scientific community by addressing currently unanswered questions that are of global relevance and have not been widely studied. These research projects will address data gaps that exist in identifying and measuring PAHs and other emerging chemicals of concern in the environment, through the development and application of state-of-the-art analytical methods. These research projects will provide new data characterizing complex PAH mixtures and their combined toxicodynamic mechanisms. These projects will also provide important new data on toxicokinetics of PAHs, including risks associated with exposures in early life stages. The RTC will serve as a catalyst to translate these research outcomes in ways that make meaningful contributions to the assessment of health risks in individuals as well as populations. The Leaders of the RTC collectively have experience in toxicology, epidemiology, environmental health, educational outreach, and public health practice. The RTC Leaders will apply their knowledge and experience to effectively communicate the SBRP research outcomes to stakeholders including public health and regulatory agencies, the scientific community, and populations at risk. The RTC will interact with and serve the Administrative Core and Research Project Leaders throughout the duration of the project period by communicating ways in which the SBRP can most effectively execute innovative research that will be of maximum utility to key stakeholders. In addition, the RTC will make important contributions to coordinate and communicate information about the SBRP at Oregon State University to the NIEHS.