Core B: Research Translation Core (Sudakin)

项目摘要(见说明)：研究翻译核心(RTC)促进了俄亥俄州立大学SRP内部的互动，并作为SRP与我们的利益相关者、NIEHS和其他SRP中心的主要接口。RTC的四项主要活动包括与政府机构发展伙伴关系、技术转让、在SRP内进行交流以及向广大受众传播信息。RTC已经与监管执法部门和公共卫生官员建立了关系，这些官员在波特兰港和下杜瓦米什超级基金网站拥有权益。在下一个项目期间，RTC将扩大关系，将OSU SRP研究的重点放在全美超级基金地点发现的多环芳烃和其他污染物的评估、监测和环境健康影响上。技术转让活动将包括在超级基金地点使用PSD进行环境监测，以及它们在人类健康风险评估中的潜在应用。RTC将合作并开发生物影响指标，监管官员可以使用这些指标来监控超级基金的现场补救活动。我们将促进我们生物医学项目的科学性，向EPA和其他风险评估人员通报我们的研究结果对评估多环芳烃混合物的人类健康风险所暗示的意义。RTC将在超级基金网站上准备与当前问题相关的教育材料和数据资源，并向广大受众有效地传播信息。我们将开发一种新的基于网络的搜索工具，提供美国各地与超级基金相关的问题和网站的全面数据。RTC将促进SRP内外的沟通，增加利益相关者互动和影响的机会，并向NIEHS和其他SRP中心报告成果。我们将组织一系列研讨会，提高学员和中心调查员对超级基金现场问题的认识，并强调俄亥俄州立大学SRP研究对决策的影响。我们计划在一年两次的电子时事通讯中总结SRP的翻译成就，我们将分发给其他SRP计划、当前和潜在的利益相关者以及NIEHS。RTC将维护一个动态网站，提供SRP活动的最新信息、我们系列研讨会的访问权限以及我们学员的简介。

PROJECT SUMMARY (See instructions): The Research Translation Core (RTC) facilitates interaction within the SRP at OSU and serves as the SRP's main interface with our stakeholders, NIEHS, and other SRP Centers. The four main activities of the RTC include developing partnerships with government agencies, technology transfer, communicating within SRP, and disseminating information to a broad audience. The RTC has established relationships with regulatory enforcement and public health officials with interests in the Portland Harbor and Lower Duwamish Superfund Sites. In the next project period, the RTC will expand relationships to focus OSU SRP research on the assessment, monitoring and environmental health implications of PAHs and other contaminants found at Superfund sites throughout the United States. Technology transfer activities will include the use of PSDs for environmental monitoring at Superfund sites, and their potential applications in human health risk assessment. The RTC will collaborate and develop biological impact metrics which regulatory officials can use to monitor Superfund site remediation activities. We will promote the science of our biomedical projects to inform EPA and other risk assessors what our research findings imply for assessment of human health risks from PAH mixtures. The RTC will prepare educational materials and data resources relevant to current issues at Superfund Sites and disseminate information effectively to a broad audience. We will develop a new web-based search tool that provides comprehensive data about Superfund-related issues and sites throughout the United States. The RTC will facilitate communications within and outside the SRP, enhance opportunities for stakeholder interactions and impact, and report achievements to NIEHS and other SRP Centers. We will organize a seminar series that enhances trainee and center investigator awareness of Superfund site issues and emphasizes the impacts of OSU SRP research on decision-making. We plan to summarize the SRP'S translation achievements in a biannual electronic newsletter that we will distribute to other SRP programs, current and potential stakeholders, and NIEHS. The RTC will maintain a dynamic website providing updates on SRP activities, access to our seminar series, and profiles of our trainees.