Emerging Viruses: Disease Models and Strategies for Vaccine Development

新兴病毒：疾病模型和疫苗开发策略

• 批准号: 8398830
• 负责人: Kimberly Weiss Schuenke
• 金额: $ 0.7万
• 依托单位: UNIVERSITY OF TEXAS MED BR GALVESTON
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-07-01 至 2013-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8398830
• 关键词: Address; Air; Animal Model; Animals; Applications Grants; Authorization documentation; Award; Development; Disabled Persons; Disease; Disease model; Emerging Communicable Diseases; Endowment; Faculty; Fostering; Funding; Goals; Grant; Health; Human; Human Pathology; Immune; Laboratories; Letters; Minority; Minority Groups; National Institute of Allergy and Infectious Disease; Nature; Participant; Pathogenesis; Prophylactic treatment; Public Health; Research; Research Personnel; Scientist; Simulate; Site; Societies; Staging; Strategic Planning; Technology; Texas; Therapy Evaluation; Time; Transportation; Travel; Underrepresented Minority; United States National Institutes of Health; Vaccine Adjuvant; Vaccine Research; Vaccines; Viral; Viral Vaccines; Virus; Virus Diseases; Woman; Work; Zoonoses; abstracting; biodefense; cost; graduate student; human disease; meetings; member; posters; programs; public health relevance; research and development; response; symposium; vaccine development

Description (as provided by the applicant): The symposium, "Emerging Viruses: Disease Models and Strategies for Vaccine Development" will bring together researchers with diverse expertise in various aspects of emerging and re-emerging viral zoonoses to address important but unexplored issues pertaining to rational vaccine development. UTMB's Center for Biodefense and Emerging Infectious Diseases was recently awarded a grant from the McLaughlin Endowment at UTMB to partially support this conference. The additional funding we seek from the NIH with this grant application will contribute to all the meeting costs, which will ultimately support NIAID's Strategic Plan for Biodefense Research by encouraging productive scientific exchanges among scientists engaged in vaccine development research for diseases caused by zoonotic viruses, including many of biodefense importance. The specific objectives of the conference are: Objective 1. To provide a forum for approximately 150 participants from academic, governmental, and industrial laboratories in the US to foster scientific exchange and share the latest advances on vaccines for viral zoonoses. The program will feature six keynote speakers as well as invited talks by leaders in the field. In addition, short talks by junior investigators and trainees will be chosen from among the submitted abstracts. Objective 2. To present a program that captures the most significant advances in the field of vaccine development for emerging and re-emerging viral diseases, including new platform technologies, the use of adjuvants, vaccines for both prophylaxis and as therapy, and the evaluation of responses to vaccines, including the elucidation of protective immune mechanisms. Central to discussions of strategies for advancing vaccine research will be in-depth sessions on the human pathology of viral diseases and whether currently available animal models are adequate for simulating human disease. Objective 3. To promote interactions among junior-level scientists and well-established researchers, accomplished primarily through poster presentations. Selected junior investigators will also be chosen to present their research in podium sessions. Objective 4. To provide travel grants for junior-level scientists, including graduate students, postdoctoral associates, and early-stage faculty members, who are engaged in research on emerging and re-emerging viral zoonoses. Half of the awards will be designated for minorities, women, or persons with disabilities. A travel grant committee will review all applications and make the determination as to how the awards are selected. Funds will be provided as reimbursements for air travel by coach class, hotel, ground transportation, and meeting registration. Objective 5. To provide an opportunity for women, members of under-represented minority groups, and persons with disabilities to engage and actively participate in a meeting that showcases their work and facilitates interactions with other scientists in their fields. The conference will be held on October 23 and 24, 2012 at the Moody Gardens Hotel and Conference Center in Galveston, Texas. Tours of the Galveston National Laboratory will be offered following the meeting. Public Health Relevance: Viruses from nature are an ever-increasing threat to human and animal health, and they effectively circumvent political boundaries and other borders that define our global societies. The "Emerging Viruses: Disease Models and Strategies for Vaccine Development" symposium will offer an opportunity for vaccine researchers and virologists to gather to discuss their latest research, including the latest developments in the use of animals as disease models. Over the two-day meeting, the most recent advances will be emphasized, and networking opportunities will allow for a productive interchange among well established and younger scientists that will contribute to the improvement of biodefense and public health.

描述（如申请人提供）：研讨会，“新兴病毒：疾病模型和疫苗开发策略”将在新兴和重新出现病毒人头的各个方面具有多种专业知识的研究人员聚集在一起，以解决重要但未开发的与合理疫苗开发有关的问题。 UTMB的生物充沛和新兴传染病中心最近获得了UTMB的麦克劳克林捐赠基金的赠款，以部分支持本次会议。我们从NIH中寻求此赠款申请的额外资金将有助于所有会议费用，这将最终通过鼓励从事生物性科学交流的生产性科学交流来支持NIAID的战略计划，从事生产性科学交流，从事疫苗开发研究，从事疫苗开发研究对人畜共动性病毒引起的疾病，包括许多生物污染物的重要性。会议的具体目标是：目标1。为美国大约150名学术，政府和工业实验室的参与者提供一个论坛，以促进科学交流并分享有关病毒人畜共患病疫苗的最新进展。该计划将以六个主题演讲者以及该领域的领导者的邀请演讲为特色。此外，将从提交的摘要中选择初级调查人员和学员的简短会谈。目的2。提出一项程序，该计划捕获了疫苗开发领域最重大的进步，用于新兴和重新出现病毒疾病，包括新的平台技术，使用佐剂的使用，预防性和作为治疗的疫苗以及对疫苗的评估，包括对疫苗的评估，包括保护性神经质机制。讨论推进疫苗研究策略的核心将是关于病毒疾病的人类病理学的深入课程，以及当前可用的动物模型是否足以模拟人类疾病。目标3。促进初级科学家和良好研究人员之间的互动，主要是通过海报演示来完成的。选定的初级研究人员还将被选中以介绍他们在讲台课程中的研究。目标4。为初级科学家提供旅行赠款，包括研究生，博士后员工和早期教职员工，他们从事有关新兴和重新出现病毒人畜共患病的研究。一半的奖项将被指定为少数民族，妇女或残疾人。旅行赠款委员会将审查所有申请，并确定如何选择奖励。将通过教练班，酒店，地面运输和会议注册提供资金作为航空旅行的报销。目标5。为了为妇女，代表性不足的少数群体成员以及残疾人的机会提供机会，以参与并积极参与一次会议，以展示她们的工作并促进与该领域的其他科学家的互动。会议将于2012年10月23日至24日在德克萨斯州加尔维斯顿的穆迪花园酒店和会议中心举行。会议结束后，将提供加尔维斯顿国家实验室的游览。 公共卫生相关性：来自自然的病毒是对人类和动物健康的不断增长的威胁，它们有效地规避了定义我们全球社会的政治边界和其他边界。 “新兴病毒：疫苗开发的疾病模型和策略”研讨会将为疫苗研究人员和病毒学家提供一个机会，以讨论其最新研究，包括使用动物作为疾病模型的最新发展。在为期两天的会议中，将强调最新进步，网络机会将使建立良好和年轻的科学家之间的富有成效的交流，这将有助于改善Biodefense和Biodefense and Public Health。