The Microcirculation in Acute Infections: A Symposium in Honor of David H. Walker, MD

急性感染中的微循环：纪念医学博士 David H. Walker 的研讨会

• 批准号: 8902599
• 负责人: Kimberly Weiss Schuenke
• 金额: $ 0.7万
• 依托单位: UNIVERSITY OF TEXAS MED BR GALVESTON
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-03-01 至 2016-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8902599
• 关键词: 3-Dimensional; Acute; Acute Disease; Affect; Air; Animal Disease Models; Antigen Presentation; Area; Authorization documentation; Award; Bacterial Infections; Blood Vessels; Blood capillaries; Cell Line; Cells; Coagulation Process; Collaborations; Communicable Diseases; Development; Disabled Persons; Edema; Educational workshop; Endothelium; Faculty; Fostering; Funding; Goals; Grant; Hemorrhage; Human; Image; Immune response; Infection; Inflammation; Knowledge; Laboratories; Letters; Life; Lung; Medical; MicroRNAs; Microcirculation; Minority; Minority Groups; Modeling; Morbidity - disease rate; National Institute of Allergy and Infectious Disease; Neuraxis; Organ; Outcome; Oxidative Stress; Parasitic Diseases; Participant; Permeability; Play; Public Health; Regulation; Research; Research Personnel; Role; Scientist; Site; Staging; Technology; Texas; Therapeutic; Time; Tissue Engineering; Tissue Model; Transportation; Travel; Underrepresented Minority; Universities; Update; Virus Diseases; Walkers; Woman; Work; abstracting; angiogenesis; arteriole; base; capillary; graduate student; meetings; member; mortality; mouse model; posters; programs; public health relevance; symposium; trafficking; venule

 DESCRIPTION (provided by the applicant): The symposium, "The Microcirculation in Acute Infections" will bring together researchers with diverse expertise in various aspects of the microcirculation, particularly in regard to acute viral, bacterial, and parasitic diseases that caue significant morbidity and mortality in humans. The specific objectives of the conference are: Objective 1. To provide a forum for approximately 200 participants from academic, governmental, and industrial laboratories in the US and abroad to foster scientific exchange and share the latest advances on various aspects of microvascular inflammation and permeability in the context of acute infectious diseases known to significantly affect the microcirculation/ microvasculature. The program will feature three keynote speakers as well as invited talks by leaders in the field. In addition, short talks by junior investigators and trainees will be chosen from among the submitted abstracts. Objective 2. To present a program that captures the most significant advances in perturbations of the microcirculation, particularly of the lungs and the central nervous system, owing to the potentially lethal complications that result when these two organs malfunction. The symposium will also cover diverse and highly active areas of research including cell trafficking, angiogenesis, coagulation, permeability regulation, vascular tone, oxidative stress, endothelial activation, antigen presentation, and inflammation. Central to discussions of strategies for advancing microcirculation research will be an in-depth workshop involving four breakout sessions devoted to discussions on (1) state-of- the-art imaging, (2) 3-dimensional modeling and tissue engineering, (3) the role of microRNA in the regulation of inflammation and immune responses and development of microRNA-based therapeutics, and (4) mouse models of infection. Objective 3. To promote interactions among junior-level scientists and well-established researchers, accomplished primarily through poster presentations. Selected junior investigators will also be chosen to present their research in podium sessions. Objective 4. To provide travel grants for junior-level scientists, including graduate students, postdoctoral associates, and early-stage faculty members, who are engaged in research on the important role that the microvasculature and its lining endothelium play in a wide range of acute diseases. Half of the awards will be designated for minorities, women, or persons with disabilities. A travel grant committee will review all applications and make the determination as to how the awards are selected. Funds will be provided as reimbursements for air travel by domestic coach class, hotel, ground transportation, and meeting registration. Objective 5. To provide an opportunity for women, members of under-represented minority groups, and persons with disabilities to engage and actively participate in a meeting that showcases their work and facilitates interactions with other scientists in their fields. The conference will be held on April 27-29, 2015 on the campus of the University of Texas Medical Branch in Galveston, Texas.

 描述（由申请人提供）：“急性感染中的微循环”专题讨论会将汇集在微循环各个方面具有不同专业知识的研究人员，特别是在导致人类显著发病率和死亡率的急性病毒，细菌和寄生虫病方面。会议的具体目标是：目标1。为来自美国和国外的学术，政府和工业实验室的约200名参与者提供论坛，以促进科学交流并分享在已知显著影响微循环/微血管系统的急性传染病背景下微血管炎症和渗透性各个方面的最新进展。该计划将有三位主旨发言人以及该领域领导人的邀请演讲。此外，还将从提交的摘要中选择初级研究人员和受训人员的简短谈话。目标2.提出一个程序，捕捉微循环，特别是肺和中枢神经系统的扰动的最重要的进展，由于这两个器官功能障碍时可能导致致命的并发症。研讨会还将涵盖各种高度活跃的研究领域，包括细胞运输、血管生成、凝血、渗透性调节、血管张力、氧化应激、内皮活化、抗原呈递和炎症。推进微循环研究的战略讨论的中心将是一个深入的研讨会，包括四个分组会议，专门讨论（1）最先进的成像，（2）三维建模和组织工程，（3）microRNA在炎症和免疫反应调节中的作用和基于microRNA的治疗方法的发展，以及（4）感染的小鼠模型。目标3.促进初级科学家和知名研究人员之间的互动，主要通过海报展示完成。选定的初级研究人员也将被选中在讲台上介绍他们的研究。目标4.为初级科学家提供旅行赠款，包括研究生，博士后助理和早期教师，他们从事微血管及其衬里内皮在各种急性疾病中发挥的重要作用的研究。一半的奖项将指定给少数民族、妇女或残疾人。一个旅费补助委员会将审查所有申请，并决定如何选择奖学金。资金将用于报销国内经济舱的航空旅行、旅馆、地面交通和会议登记费用。目标5.为妇女、代表性不足的少数群体成员和残疾人提供机会，让他们参与并积极参加会议，展示他们的工作，并促进与各自领域的其他科学家的互动。会议将于2015年4月27日至29日在德克萨斯州加尔维斯顿的德克萨斯大学医学分支校园举行。