The Microcirculation in Acute Infections: A Symposium in Honor of David H. Walker, MD

急性感染中的微循环：纪念医学博士 David H. Walker 的研讨会

• 批准号: 8902599
• 负责人: Kimberly Weiss Schuenke
• 金额: $ 0.7万
• 依托单位: UNIVERSITY OF TEXAS MED BR GALVESTON
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-03-01 至 2016-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8902599
• 关键词: 3-Dimensional; Acute; Acute Disease; Affect; Air; Animal Disease Models; Antigen Presentation; Area; Authorization documentation; Award; Bacterial Infections; Blood Vessels; Blood capillaries; Cell Line; Cells; Coagulation Process; Collaborations; Communicable Diseases; Development; Disabled Persons; Edema; Educational workshop; Endothelium; Faculty; Fostering; Funding; Goals; Grant; Hemorrhage; Human; Image; Immune response; Infection; Inflammation; Knowledge; Laboratories; Letters; Life; Lung; Medical; MicroRNAs; Microcirculation; Minority; Minority Groups; Modeling; Morbidity - disease rate; National Institute of Allergy and Infectious Disease; Neuraxis; Organ; Outcome; Oxidative Stress; Parasitic Diseases; Participant; Permeability; Play; Public Health; Regulation; Research; Research Personnel; Role; Scientist; Site; Staging; Technology; Texas; Therapeutic; Time; Tissue Engineering; Tissue Model; Transportation; Travel; Underrepresented Minority; Universities; Update; Virus Diseases; Walkers; Woman; Work; abstracting; angiogenesis; arteriole; base; capillary; graduate student; meetings; member; mortality; mouse model; posters; programs; public health relevance; symposium; trafficking; venule

 DESCRIPTION (provided by the applicant): The symposium, "The Microcirculation in Acute Infections" will bring together researchers with diverse expertise in various aspects of the microcirculation, particularly in regard to acute viral, bacterial, and parasitic diseases that caue significant morbidity and mortality in humans. The specific objectives of the conference are: Objective 1. To provide a forum for approximately 200 participants from academic, governmental, and industrial laboratories in the US and abroad to foster scientific exchange and share the latest advances on various aspects of microvascular inflammation and permeability in the context of acute infectious diseases known to significantly affect the microcirculation/ microvasculature. The program will feature three keynote speakers as well as invited talks by leaders in the field. In addition, short talks by junior investigators and trainees will be chosen from among the submitted abstracts. Objective 2. To present a program that captures the most significant advances in perturbations of the microcirculation, particularly of the lungs and the central nervous system, owing to the potentially lethal complications that result when these two organs malfunction. The symposium will also cover diverse and highly active areas of research including cell trafficking, angiogenesis, coagulation, permeability regulation, vascular tone, oxidative stress, endothelial activation, antigen presentation, and inflammation. Central to discussions of strategies for advancing microcirculation research will be an in-depth workshop involving four breakout sessions devoted to discussions on (1) state-of- the-art imaging, (2) 3-dimensional modeling and tissue engineering, (3) the role of microRNA in the regulation of inflammation and immune responses and development of microRNA-based therapeutics, and (4) mouse models of infection. Objective 3. To promote interactions among junior-level scientists and well-established researchers, accomplished primarily through poster presentations. Selected junior investigators will also be chosen to present their research in podium sessions. Objective 4. To provide travel grants for junior-level scientists, including graduate students, postdoctoral associates, and early-stage faculty members, who are engaged in research on the important role that the microvasculature and its lining endothelium play in a wide range of acute diseases. Half of the awards will be designated for minorities, women, or persons with disabilities. A travel grant committee will review all applications and make the determination as to how the awards are selected. Funds will be provided as reimbursements for air travel by domestic coach class, hotel, ground transportation, and meeting registration. Objective 5. To provide an opportunity for women, members of under-represented minority groups, and persons with disabilities to engage and actively participate in a meeting that showcases their work and facilitates interactions with other scientists in their fields. The conference will be held on April 27-29, 2015 on the campus of the University of Texas Medical Branch in Galveston, Texas.

 描述（由适用提供）：“急性感染的微循环”研讨会将在微循环的各个方面具有多种专业知识的研究人员聚集在一起，尤其是在急性病毒，细菌和寄生虫疾病方面，这些疾病会导致人们在人类的发病率和死亡率上有明显的发病率和死亡率。会议的具体目标是：目标1。为美国和国外的大约200名参与者提供一个论坛，以促进科学交流，并分享有关微血管感染和渗透性各个方面的最新进展，并在急性感染性疾病的背景下对微骨骼/微循环/微骨骼造成的显着影响。该计划将以三个主题演讲者以及该领域的领导者的邀请演讲为特色。此外，将从提交的摘要中选择初级调查人员和学员的简短会谈。目的2。提出一项程序，该程序在微循环的扰动中，尤其是肺部和中枢神经系统的扰动方面取得了最大的进步，这是由于这两个器官故障时可能导致的致命并发症。研讨会还将涵盖潜水员和高度活跃的研究领域，包括细胞运输，血管生成，凝结，渗透率调节，血管张力，氧化应激，内皮激活，抗原表现和注射。讨论进行微循环研究策略的核心将是一个深入的研讨会，涉及四次突破性会议，该课程专门讨论（1）最先进的成像，（2）3维建模和组织工程，（3）MicroRNA在Infection and MicroRNORNAS基于MicroRNORNA基于鼠标的典范中的作用，并（4目标3。促进初级科学家和良好研究人员之间的互动，主要是通过海报演示来完成的。选定的初级研究人员还将被选中以介绍他们在讲台课程中的研究。目标4。为初级科学家提供旅行赠款，包括研究生，博士后员工和早期教职员工，他们研究了微脉管系统及其内皮在各种急性疾病中发挥的重要作用。一半的奖项将被指定为少数民族，妇女或残疾人。旅行赠款委员会将审查所有申请，并确定如何选择奖励。资金将以国内教练班，酒店，地面运输和会议注册为航空旅行提供资金。目标5。为了为妇女，代表性不足的少数群体的成员以及残疾人的机会提供机会，并积极参与一次会议，以展示她们的工作并促进与该领域的其他科学家的互动。该会议将于2015年4月27日至29日在德克萨斯州加尔维斯顿的德克萨斯大学医学分公司校园举行。