Utah Population Database Shared Resource

犹他州人口数据库（UTB）拥有大约1200万条记录，其中包含大量的 犹他州的家谱与大量的医疗记录（包括癌症记录）和其他类型的数据有关。 它支持90多个研究项目，是遗传学，流行病学， 人口统计学和公共卫生研究。除了来自犹他州的家谱和癌症登记数据外， 爱达荷州，CSB与住院医院记录和生命记录有关，包括犹他州死亡证明。这些 这些数据可以确定癌症的家族聚集性。研究可能有一个研究设计， 结合亲属关系/谱系结构或使用病例控制结果方法。软件已 开发了一种易于为研究人员提供有关癌症风险，隔离模式和 血统大小。 CNOB共享资源的目标是执行以下操作： 通过每年更新和链接全州范围的记录来维护CSB研究基础设施，包括 癌症、生命记录、驾驶执照数据和住院事件 方便访问犹他州大学企业数据仓库中的医疗信息 健康科学中心和山间医疗保健，以及犹他州卫生部 维护谱系基础设施和分析工具 提供获得生物多样性和专业知识，在其使用，以支持研究项目 â为研究项目提供持续的信息，例如死亡和癌症复发 这些活动所需的资源超出了任何单一研究项目的范围。分享的blog 资源使大型数据集和多代系谱可用，同时仔细保护 个人层面的数据隐私。所有项目均需IRB批准。此外，犹他州遗传资源 和流行病学研究通过另一个审查程序管理对CNOB的访问。 基因组学是跨学科和协作癌症研究的焦点，因为基因发现涉及到 基础和临床研究人员。来自亨斯迈癌症研究所多个项目的研究人员， 许多大学的系都使用这种计算机。该数据库是美国唯一的此类数据库， 这是世界上为数不多的资源之一。 Geraldine Mineau博士自1994年以来一直指导着CQB。CIMB是一家由癌症中心管理的机构， HCI董事的监督。有一个教师咨询委员会;一项调查已被用来评估 用户满意度。CNOB位于癌症中心空间，随时可以接触到研究人员。2008年， 10%的CNOB使用者是通过同行评审获得资金的成员。请CCSG提供资金 以支付拟议的联合国开发计划署预算的10%（139，875美元）。

The Utah Population Database (UPDB) holds approximately 12 million records in which an extensive set of Utah genealogies is linked to large sets of medical records (including cancer records) and other types of data. It supports more than 90 research projects and is a rich research resource for genetic, epidemiological, demographic, and public health studies. In addition to genealogies and Cancer Registry data from Utah and Idaho, UPDB is linked to inpatient hospital records and vital records, including Utah death certificates. These data allow the identification of familial clustering of cancer. Studies may have a research design that incorporates kinship/pedigree structure or that uses a case control outcomes approach. Software has been developed that readily provides researchers information about cancer risk, segregation patterns, and pedigree size. The goals of the UPDB Shared Resource are to do the following: ¿ Maintain the UPDB research infrastructure by annually updating and linking statewide records, including cancer, vital records, driver license data, and inpatient hospital events ¿ Facilitate access to medical information in the enterprise data warehouses of the University of Utah Health Sciences Center and Intermountain Healthcare, as well as the Utah Department of Health ¿ Maintain pedigree infrastructure and analysis tools ¿ Provide access to UPDB and expertise in its use to support research projects ¿ Provide ongoing information such as deaths and cancer recurrence to research projects These activities require resources beyond the scope of any single research project. The UPDB Shared Resource makes large datasets and multigenerational pedigrees available, while carefully protecting the privacy of individual-level data. All projects require IRB approval. In addition, the Utah Resource for Genetic and Epidemiology Research administers access to UPDB through another review process. UPDB is a focal point of transdisciplinary and collaborative cancer research, since gene discovery involves both basic and clinical researchers. Investigators from multiple Huntsman Cancer Institute Programs and many University departments use the UPDB. The UPDB is the only such database in the United States and one of few such resources in the world. Geraldine Mineau, PhD, has directed the UPDB since 1994. UPDB is a Cancer Center-managed facility with supervision from HCI Directors. There is a Faculty Advisory Committee; a survey has been used to assess user satisfaction. UPDB is located in Cancer Center space with ready access to investigators. In 2008, 45 percent of UPDB usage was by members with peer-reviewed funding. Funds are requested from the CCSG to cover 10 percent ($139,875) of the proposed UPDB budget.