CCR Office of Training and Education

CCR培训教育办公室

• 批准号: 8554231
• 负责人: Jonathan Scott Wiest
• 金额: $ 354.1万
• 依托单位: DIVISION OF BASIC SCIENCES - NCI
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8554231
• 关键词: Academia; Address; Advisory Committees; Agreement; Archives; Area; Automation; Awareness; Biology; Clinic; Clinical; Clinical Oncology; Collaborations; Communities; Conflict (Psychology); Contractor; Contracts; Critical Pathways; Development; Devices; Disadvantaged; Doctor of Philosophy; Drug Industry; Educational process of instructing; Educational workshop; Exposure to; Extramural Activities; Faculty; Fellowship; Funding Mechanisms; Goals; Government Agencies; Grant; Hour; Illinois; Individual; Industry; Institutes; Internet; Internships; K-Series Research Career Programs; Laboratories; Learning; Malignant Neoplasms; Manuscripts; Maryland; Medical; Mentors; Michigan; Mission; Molecular Target; NCI Center for Cancer Research; National Cancer Institute; National Heart, Lung, and Blood Institute; National Institute of Allergy and Infectious Disease; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Neurological Disorders and Stroke; North Carolina; Oral; Oxidation-Reduction; Pharmaceutical Preparations; Policies; Population; Positioning Attribute; Postdoctoral Fellow; Principal Investigator; Process; Recruitment Activity; Regimen; Regulation; Research; Research Personnel; Resources; Rewards; Safety; Science; Scientist; Staging; Stress; Students; Technology; Testing; Training; Training Programs; Training and Education; Translational Research; Underrepresented Minority; United States Food and Drug Administration; United States National Institutes of Health; Universities; Veterinary Medicine; Work; Writing; anticancer research; bench to bedside; career; comparative; design; drug discovery; editorial; experience; graduate student; high throughput screening; improved; interest; lecturer; lectures; meetings; member; molecular pathology; oncology; operation; peer; posters; product development; programs; skills; statistics; tumor

The Center for Cancer Research (CCR) Office of Training and Education (OTE) mission is to have a programmatic impact on the overall training experience of the basic scientists, clinical fellows, and other trainees at CCR/NCI. The OTE addresses many of needs in the trainee population, but continues to expand on these activities. Outlined below are some of the more important functions and activities within OTE. Special Fellow ActivitiesThe OTE serves as a liaison to the postdoctoral community and the CCR Office of the Director. A postdoctoral association and a steering committee were developed many years ago. The committee plans and holds the annual CCR Fellows and Young Investigators Colloquium. Nationally and internationally recognized speakers are invited for plenary sessions. The retreat is designed as vehicle to encourage the fellows to network with their peers and to develop independent collaborations. It also serves as a forum for presenting their research in a formal setting as posters or oral presentations. OTE also developed the Fellows Editorial Board to serve the needs of the community. The board meets weekly and has reviewed over 500 manuscripts. The board provides an opportunity for the fellows to improve their own writing skills, learn in depth editorial skills, and consider scientific editing as a career option. The board has been in operation several years and former members have transitioned to positions in this field. The board has been so successful that it has opened its membership and manuscript process to fellows from all other NIH institutes. Course developmentWe have developed numerous courses to address deficiencies and these include cancer and redox biology, statistics, the culture of industry and management. Most of these courses are offered annually and are team taught by NCI investigators or outside contractors. Formats range from once per week for a semester to multiple half or full day classes. All the courses and lecturers are evaluated and changes are made as needed. One of the more successful courses is Translational Research in Clinical Oncology (TRACO). In TRACO we have two one-hour lectures each week with a clinical and a basic scientist presenting on a single tumor type or critical pathway. The lectures provide an understanding of how bench research is moved to the clinic and implemented. TRACO is 15 weeks long and over 150 postdoctoral fellows and principal investigators register each year. It is also web cast and the lectures are archived for viewing at the convenience of the students. We also offer a workshop in grant writing. The K grant mechanisms allow our intramural postdoctoral fellows to apply during their tenure at the NCI and facilitate their transition to independent faculty positions. During this workshop we have NCI Extramural Program Directors introduce the review process and contract a scientific writer to hold a workshop on ?selling their science?. The weekly meeting critically reviews each application and the importance of the hypothesis and specific aims are stressed. All the fellows reviewing each other?s application re-enforces the learning process and they think more critically about their own applications. University PartnershipsThe NIH developed the Graduate Partnership Program (GPP) several years ago as a mechanism to bring graduate students to campus in formalized NIH/University partnerships. We leveraged this program to build the Comparative Molecular Pathology program. This program trains recent graduates in veterinary medicine in a Ph.D. from one of the four partner universities and includes the University of Illinois, Michigan State University, North Carolina State University, and the University of Maryland. Since the inception of the program, four other NIH institutes (NIAID, NIDDK, NINDS, and NHLBI) have signed interagency agreements to support and partner with our program. A second partnership is the Molecular Targets and Drug Discovery Technologies Master?s degree with Johns Hopkins University. This program focuses on several faucets of high throughput screening and laboratory automation. A feature of the program is a fellowship component recruiting post-baccalaureates to CCR laboratories working on projects related to the CCR Molecular Targets Initiative. NCI/FDA Interagency Oncology Task Force Training Fellowship The National Cancer Institute and the U.S. Food and Drug Administration (FDA) developed fellowship training for scientists and clinicians in research and research-related regulatory review. The objective of the NCI-FDA fellowships is to train a cadre of scientists in research and research-related regulatory review, policies, and regulations so they develop a skill set bridging the two disparate processes. Fellows learn to build awareness of regulatory requirements into the early stages of the medical product development process and develop strategies to improve planning throughout research and regulatory review. Graduates of this program develop skills of value to academia, the pharmaceutical industry, and government agencies. If heightened awareness of the requirements of regulatory review of safety and efficacy can be incorporated into the schema of development and testing from the early stages, NCI and FDA will be better equipped to achieve a common goal: bringing safe and effective drugs, regimens, and devices from the bench to the bedside as quickly as possible. Cancer Research Interns (CRI)The OTE has developed a program to bring under represented minorities or individuals from disadvantaged backgrounds to CCR laboratories for a first research experience. The Cancer Research Interns program (CRI) is supported by the CCR Office of the Director and allows us to place and provide stipend support for the students without previous research experience. This program allows us to build a pipeline for underrepresented minorities with an interest in research. Over the course of this program, many of the students continued in CCR labs for additional training or were able to use their experience to gain an offer to return to other NIH laboratories. Therefore this program is beginning to build an increased diversity within our trainee population and will provide opportunities for students who would never have received these chances in the past.Career Guidance and MentoringOur office serves as a resource to the trainees for career guidance and as second mentors. We frequently meet with CCR fellows to discuss career paths and provide information on various opportunities. These may include internships or other mechanisms for training that would help to build their CVs in these other arenas. We are also a resource to CCR investigators when there are conflicts within their labs or between themselves and their trainees. In some cases we facilitate transferring a fellow from one lab to another in an effort to improve the situation.

癌症研究中心（CCR）培训与教育办公室（OTE）的使命是对CCR/NCI的基础科学家、临床研究员和其他受训者的整体培训体验产生计划性影响。OTE解决了受训人员的许多需求，并继续扩大这些活动。下面概述了OTE的一些更重要的功能和活动。特别研究员活动OTE是博士后社区和主任CCR办公室的联络人。多年前成立了博士后协会和指导委员会。委员会计划并举办年度CCR研究员和青年研究人员座谈会。邀请国内和国际公认的发言者参加全体会议。该静修活动旨在鼓励学员与同行建立联系，并发展独立合作。它还作为一个论坛，以海报或口头报告的形式在正式的环境中展示他们的研究。OTE也发展了研究员编辑委员会来服务社区的需要。委员会每周召开一次会议，审查了500多份手稿。该委员会为研究员提供了一个机会，以提高他们自己的写作技巧，深入学习编辑技巧，并考虑将科学编辑作为一种职业选择。该委员会已运作多年，前成员已过渡到该领域的职位。该委员会非常成功，它已经向所有其他NIH研究所的研究员开放了其成员资格和手稿流程。我们已经开发了许多课程来解决不足之处，包括癌症和氧化还原生物学、统计学、工业文化和管理。这些课程大部分每年都开设一次，由NCI调查人员或外部承包商团队授课。形式从一个学期每周一次到多个半天或全天的课程。所有的课程和讲师都经过评估，并根据需要进行更改。其中比较成功的课程是临床肿瘤学转化研究（TRACO）。在TRACO，我们每周有两个一小时的讲座由一位临床科学家和一位基础科学家介绍一种肿瘤类型或关键途径。讲座提供了如何将实验室研究转移到临床和实施的理解。TRACO为期15周，每年有150多名博士后和首席研究员注册。它也是网络直播和讲座存档，以方便学生观看。我们也提供了一个关于基金写作的工作坊。K资助机制允许我们的校内博士后在NCI任职期间申请，并促进他们过渡到独立的教师职位。在这个研讨会上，我们有NCI的校外项目主任介绍审查过程，并签约一位科学作家举办研讨会？出卖他们的科学？每周会议严格审查每个应用程序，并强调假设和具体目标的重要性。所有的同学都在互相评价？S应用程序强化了学习过程，他们对自己的应用程序进行了更批判性的思考。大学伙伴关系几年前，美国国立卫生研究院制定了研究生伙伴关系计划（GPP），作为一种机制，将研究生带到美国国立卫生研究院/大学正式合作伙伴关系的校园。我们利用这个项目建立了比较分子病理学项目。该项目为来自伊利诺伊大学、密歇根州立大学、北卡罗来纳州立大学和马里兰大学等四所合作大学之一的兽医专业应届毕业生提供博士学位培训。自该计划开始以来，NIH的其他四个研究所（NIAID， NIDDK， NINDS和NHLBI）签署了机构间协议，以支持和合作我们的计划。第二个合作伙伴是分子靶标和药物发现技术硕士？他获得了约翰霍普金斯大学的学位。该计划侧重于高通量筛选和实验室自动化的几个龙头。该计划的一个特点是奖学金组成部分，招募学士学位后的毕业生到CCR实验室从事与CCR分子目标计划相关的项目。美国国家癌症研究所和美国食品和药物管理局（FDA）为研究和与研究相关的监管审查方面的科学家和临床医生提供了奖学金培训。NCI-FDA奖学金的目标是在研究和与研究相关的监管审查、政策和法规方面培训一批骨干科学家，以便他们培养一套连接这两个不同过程的技能。研究员将学习在医疗产品开发过程的早期阶段建立对监管要求的认识，并制定战略，以改进整个研究和监管审查的规划。该课程的毕业生培养对学术界、制药业和政府机构有价值的技能。如果提高对安全性和有效性监管审查要求的认识可以从早期阶段纳入开发和测试的方案中，NCI和FDA将更好地实现一个共同目标：将安全有效的药物、方案和设备尽快从实验室带到床边。癌症研究实习生（CRI） OTE制定了一项计划，将代表性不足的少数民族或来自弱势背景的个人带到CCR实验室，获得首次研究经验。癌症研究实习生计划（CRI）由CCR主任办公室支持，允许我们为没有先前研究经验的学生提供安置和津贴支持。这个项目让我们能够为对研究感兴趣的少数族裔建立一个渠道。在这个项目的过程中，许多学生继续在CCR实验室接受额外的培训，或者能够利用他们的经验获得返回NIH其他实验室的机会。因此，这个项目开始在我们的学员群体中建立一个越来越多样化的群体，并将为过去从未获得过这些机会的学生提供机会。职业指导和指导我们的办公室为学员提供职业指导和第二导师。我们经常与CCR成员会面，讨论职业道路，并提供各种机会的信息。这些可能包括实习或其他培训机制，这将有助于他们在这些其他领域建立简历。当CCR研究人员在实验室内部或他们与学员之间发生冲突时，我们也是他们的资源。在某些情况下，为了改善这种情况，我们会帮助一个人从一个实验室转到另一个实验室。