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Evidence for Establishing Optimum Protein Intake in Older Adults

确定老年人最佳蛋白质摄入量的证据

基本信息

批准号：
8402416
负责人：
Jeannette Michele Beasley
金额：
$ 24.89万
依托单位：
ALBERT EINSTEIN COLLEGE OF MEDICINE
依托单位国家：
美国
项目类别：
财政年份：
2012
资助国家：
美国
起止时间：
2012-02-01 至 2015-01-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8402416
关键词：
Address Adult Aged, 80 and over Aging Award Benefits and Risks Biological Markers Biological Preservation Biology of Aging Body Weight Chronic Disease Chronic Kidney Failure Clinical Research Creatinine Data Data Analyses Data Set Diet Dietary Assessment Dietary Proteins Eating Elderly Energy Intake Environment Epidemiology Food Fred Hutchinson Cancer Research Center Frequencies Funding Guidelines Health Individual Institutes K-Series Research Career Programs Kilogram Measurement Measures Mentors Morbidity - disease rate National Research Service Awards North Carolina Nutrient Nutritional Outcome Participant Patient Self-Report Performance Phase Physical Function Population Proteins Public Health Questionnaires Recommendation Recommended Dietary Allowance Renal function Research Research Institute Research Personnel Research Project Summaries Scientist Thesauri Time Training Translating Universities Update Visit Walking Woman Women&apos s Health World Health Organization aged base career clinically relevant cohort design epidemiologic data evidence base experience grasp improved nitrogen balance novel nutrition population based post gamma-globulins programs protein intake public health relevance skills tool young man

项目摘要

Changes from the original submission Project Summary Research Project: Data from small clinical studies suggest that current protein recommendations may highlighted not be optimal for older adults, but evidence from population-based studies is sparse. During the mentored phase of the award, the candidate proposes to contribute to the emerging evidence base for establishing optimal protein intake using epidemiologic data by evaluating potential benefits and adverse associations of higher protein intake with physical function and kidney function During the independent phase of the award, Dr. Beasley will 2) administer in the Women's Health Initiative. a food frequency questionnaire to a cohort of 8,000 participants of the Women's Health Initiative Extension Study aged 80 and over older adults; 3) assess renal function in a subset of 500 women using creatinine and cystatin C; 4) measure associations between protein intake and changes in renal function and physical function using the Short Performance Physical Battery. Candidate and Environment: Dr. Beasley is a NRSA fellow funded by the National Institute of Aging at the Group Health Research Institute and a staff scientist at the Fred Hutchinson Cancer Research Center. Dr. Beasley received training in public health nutrition at the University of North Carolina at Chapel Hill and earned her doctorate in epidemiology from Johns Hopkins University. The career development award provides the additional training needed in aging and statistical analysis, so Dr. Beasley will be able to contribute scientific evidence that would help define nutrient recommendations for older adults in order to maintain physical function and reduce the burden of chronic disease.

对原始提交的更改