Molecular Basis of Immunity - Kirschstein - NRSA

免疫的分子基础 - Kirschstein - NRSA

• 批准号: 8338288
• 负责人: MADELEINE W. CUNNINGHAM
• 金额: $ 15.34万
• 依托单位: UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-09-01 至 2017-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8338288
• 关键词: Immunity; Molecular; National Research Service Awards; base

DESCRIPTION (provided by applicant): The immunologist of tomorrow must appreciate both basic and clinical immunology to effectively utilize modern tools of research in the pursuit of new knowledge about immune mediated and infectious diseases and their pathogenesis as well as for development of new vaccines and therapies against immune-mediated diseases. Training the scientist and the physician-scientist in immunology and its relationship to infectious diseases as well as to other related disciplines such as pathology, biochemistry, cell biology and biotechnology will be crucial for the future of immunological sciences. To facilitate the distribution of knowledge in the field of immunology, the Immunology Training Program goals are to provide fundamental and research training to 4 predoctoral and 2 postdoctoral fellows with an immunology faculty of 20 preceptors. The program is unique in that it encompasses faculty from the University of Oklahoma Health Sciences and the Oklahoma Medical Research Foundation as well as its strong focus on microbial as well as host immunology. The participating training faculty are particularly strong in the 4 subdisciplines emphasized in the Immunology Training Program, which include 1) Responses to Pathogens, 2) Lymphocyte Development and Signaling, 3) Inflammation, and 4) Autoimmunity. The faculty preceptors have interacted on the OUHSC campus for years, forming a network that is particularly suited to train a cohesive group of pre and postdoctoral fellows in molecular immunology. The program recruits students and fellows from national and international sources, has strong NIH funded research programs, and has new faculty and facilities, all of which foster an atmosphere of excellence in training. The predoctoral students are eligible for the training program after completion of their lab rotations and qualifying exam. The Immunology Training Program will provide in-depth enrichment in the 4 subdisciplines to the pre and postdoctoral trainees through immunology classes and retreats. Postdoctoral fellows are strongly encouraged to take coursework and to mentor predoctoral students to enhance their immunology experience. The Immunology Training Program advisory and selection committee selects the pre and postdoctoral trainees and acts in an advisory capacity. Since the beginning of the program September 1, 2001, the objectives of the program are being met to provide excellence in research, immunology course work, an immunology retreat, and an immunology journal club class for the trainees. The yearly interactive immunology retreat as well as the Immunology Journal Club class have been effective in bringing the pre and postdoctoral fellows together with the training faculty in an environment that fosters excellence. Our program has been and will continue to be important to prepare trainees for future careers in immunology. PUBLIC HEALTH RELEVANCE: The Immunology Training Program in Oklahoma will recruit and train students pursuing a PhD or MD degree (predoctoral trainees) or individuals who already have the PhD or MD degree (postdoctoral trainees) to perform medical and basic research in immunology. For example, trainees might study how infections affect the immune system such as in the study of immune responses to vaccines or how infections may lead to autoimmune diseases or how the immune system develops or responds to infections. Training in research laboratories of nationally and internationally recognized scientists along with a curriculum in immunology classes, retreats and national meetings will provide crucial training for the future immunologists in the United States.

描述（由申请人提供）：未来的免疫学家必须欣赏基础和临床免疫学，以有效地利用现代研究工具， 关于免疫介导的疾病和传染病及其发病机制的知识，以及开发针对免疫介导的疾病的新疫苗和疗法。在免疫学及其与传染病的关系方面培训科学家和医生-科学家 以及其他相关学科，如病理学、生物化学、细胞生物学和生物技术，将对免疫科学的未来至关重要。为了促进免疫学领域知识的传播，免疫学培训计划的目标是为4名博士前和2名博士后研究员提供基础和研究培训，免疫学系有20名导师。该计划的独特之处在于它包括来自俄克拉荷马州健康科学大学和俄克拉荷马州医学研究基金会的教师，以及其对微生物和宿主免疫学的强烈关注。参与培训的教师在免疫学培训计划中强调的4个子学科中特别强大，其中包括1）对病原体的反应，2）淋巴细胞发育和信号传导，3）炎症和4）自身免疫。教师导师在OUHSC校园互动多年，形成了一个网络，特别适合培养一个有凝聚力的小组的前和博士后研究员在分子免疫学。该计划从国家和国际来源招募学生和研究员，拥有强大的NIH资助的研究项目，并拥有新的教师和设施，所有这些都促进了卓越的培训氛围。博士前学生在完成实验室轮换和资格考试后有资格参加培训计划。免疫学培训计划将通过免疫学课程和务虚会为博士前和博士后学员提供4个子学科的深入充实。强烈鼓励博士后研究员参加课程，并指导博士前学生，以提高他们的免疫学经验。免疫学培训计划咨询和选拔委员会选择博士前和博士后学员，并以顾问身份行事。自2001年9月1日该计划开始以来，该计划的目标正在得到满足，以提供卓越的研究，免疫学课程工作，免疫学务虚会，和免疫学杂志俱乐部类的学员。每年的互动免疫学务虚会以及免疫学杂志俱乐部类已有效地使前和博士后研究员与培训教师在一个环境中，培养卓越。我们的计划已经并将继续是重要的准备学员在免疫学未来的职业生涯。 公共卫生相关性：俄克拉荷马州的免疫学培训计划将招募和培训攻读博士或医学博士学位的学生（博士前学员）或已经拥有博士或医学博士学位的个人（博士后学员）进行免疫学的医学和基础研究。例如，受训者可能会研究感染如何影响免疫系统，例如研究对疫苗的免疫反应，或感染如何导致自身免疫性疾病，或免疫系统如何发展或对感染作出反应。在国家和国际公认的科学家的研究实验室的培训沿着免疫学课程，务虚会和国家会议将为美国未来的免疫学家提供重要的培训。