Molecular Basis of Immunity - Kirschstein - NRSA

免疫的分子基础 - Kirschstein - NRSA

• 批准号: 8338288
• 负责人: MADELEINE W. CUNNINGHAM
• 金额: $ 15.34万
• 依托单位: UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-09-01 至 2017-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8338288
• 关键词: Immunity; Molecular; National Research Service Awards; base

DESCRIPTION (provided by applicant): The immunologist of tomorrow must appreciate both basic and clinical immunology to effectively utilize modern tools of research in the pursuit of new knowledge about immune mediated and infectious diseases and their pathogenesis as well as for development of new vaccines and therapies against immune-mediated diseases. Training the scientist and the physician-scientist in immunology and its relationship to infectious diseases as well as to other related disciplines such as pathology, biochemistry, cell biology and biotechnology will be crucial for the future of immunological sciences. To facilitate the distribution of knowledge in the field of immunology, the Immunology Training Program goals are to provide fundamental and research training to 4 predoctoral and 2 postdoctoral fellows with an immunology faculty of 20 preceptors. The program is unique in that it encompasses faculty from the University of Oklahoma Health Sciences and the Oklahoma Medical Research Foundation as well as its strong focus on microbial as well as host immunology. The participating training faculty are particularly strong in the 4 subdisciplines emphasized in the Immunology Training Program, which include 1) Responses to Pathogens, 2) Lymphocyte Development and Signaling, 3) Inflammation, and 4) Autoimmunity. The faculty preceptors have interacted on the OUHSC campus for years, forming a network that is particularly suited to train a cohesive group of pre and postdoctoral fellows in molecular immunology. The program recruits students and fellows from national and international sources, has strong NIH funded research programs, and has new faculty and facilities, all of which foster an atmosphere of excellence in training. The predoctoral students are eligible for the training program after completion of their lab rotations and qualifying exam. The Immunology Training Program will provide in-depth enrichment in the 4 subdisciplines to the pre and postdoctoral trainees through immunology classes and retreats. Postdoctoral fellows are strongly encouraged to take coursework and to mentor predoctoral students to enhance their immunology experience. The Immunology Training Program advisory and selection committee selects the pre and postdoctoral trainees and acts in an advisory capacity. Since the beginning of the program September 1, 2001, the objectives of the program are being met to provide excellence in research, immunology course work, an immunology retreat, and an immunology journal club class for the trainees. The yearly interactive immunology retreat as well as the Immunology Journal Club class have been effective in bringing the pre and postdoctoral fellows together with the training faculty in an environment that fosters excellence. Our program has been and will continue to be important to prepare trainees for future careers in immunology. PUBLIC HEALTH RELEVANCE: The Immunology Training Program in Oklahoma will recruit and train students pursuing a PhD or MD degree (predoctoral trainees) or individuals who already have the PhD or MD degree (postdoctoral trainees) to perform medical and basic research in immunology. For example, trainees might study how infections affect the immune system such as in the study of immune responses to vaccines or how infections may lead to autoimmune diseases or how the immune system develops or responds to infections. Training in research laboratories of nationally and internationally recognized scientists along with a curriculum in immunology classes, retreats and national meetings will provide crucial training for the future immunologists in the United States.

描述（由申请人提供）：未来的免疫学家必须了解基础和临床免疫学，以有效利用现代研究工具来追求新的 关于免疫介导的传染病及其发病机制以及开发针对免疫介导的疾病的新疫苗和疗法的知识。对科学家和医师科学家进行免疫学及其与传染病关系的培训 以及病理学、生物化学、细胞生物学和生物技术等其他相关学科对于免疫科学的未来至关重要。为了促进免疫学领域知识的传播，免疫学培训计划的目标是为 4 名博士前研究员和 2 名博士后研究员以及由 20 名导师组成的免疫学教师提供基础和研究培训。该项目的独特之处在于它包括来自俄克拉荷马州健康科学大学和俄克拉荷马州医学研究基金会的教师，并且重点关注微生物学和宿主免疫学。参与培训的师资队伍在免疫学培训计划强调的 4 个子学科方面尤其强大，包括 1) 对病原体的反应、2) 淋巴细胞的发育和信号传导、3) 炎症和 4) 自身免疫。教授们在 OUHSC 校园内互动多年，形成了一个特别适合培养分子免疫学领域有凝聚力的博士前和博士后团队的网络。该项目从国内外招募学生和研究员，拥有强大的 NIH 资助的研究项目，并拥有新的师资和设施，所有这些都营造了卓越的培训氛围。博士前学生在完成实验室轮转和资格考试后就有资格参加培训计划。免疫学培训计划将通过免疫学课程和静修活动，为博士前和博士后学员提供四个分支学科的深入拓展。强烈鼓励博士后研究员参加课程并指导博士前学生以增强他们的免疫学经验。免疫学培训项目咨询和选拔委员会负责挑选博士前和博士后学员，并以顾问身份行事。自 2001 年 9 月 1 日该计划开始以来，该计划的目标正在实现，即为学员提供卓越的研究、免疫学课程作业、免疫学静修和免疫学期刊俱乐部课程。每年一度的互动免疫学静修会以及免疫学期刊俱乐部课程有效地将博士前和后研究员以及培训教师聚集在一个培养卓越的环境中。我们的计划对于为学员未来从事免疫学职业做好准备一直并将继续发挥重要作用。 公共卫生相关性：俄克拉荷马州的免疫学培训计划将招募和培训正在攻读博士学位或医学博士学位的学生（博士前培训生）或已获得博士学位或医学博士学位的个人（博士后培训生），以进行免疫学方面的医学和基础研究。例如，学员可能会研究感染如何影响免疫系统，例如研究对疫苗的免疫反应或感染如何导致自身免疫性疾病或免疫系统如何发展或对感染做出反应。在国内外知名科学家的研究实验室中进行的培训以及免疫学课程、务虚会和全国会议课程将为美国未来的免疫学家提供重要的培训。