The Effects of Repeated Retrieval on Autobiographical Memories

重复检索对自传体记忆的影响

• 批准号: 8317030
• 负责人: Andrew C Butler
• 金额: $ 5.22万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-09-01 至 2015-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8317030
• 关键词: Affect; Alzheimer' s Disease; Amnesia; Arousal; Basic Science; Behavior; Behavioral; Characteristics; Clinical; Communication; Complex; Emotional; Emotions; Empirical Research; Event; Exposure to; Future; Goals; Image; Individual; Knowledge; Lead; Learning; Longevity; Measures; Memory; Mental Depression; Mental Health; National Institute of Mental Health; Nature; Obsessive-Compulsive Disorder; Participant; Personhood; Phobic anxiety disorder; Play; Post-Traumatic Stress Disorders; Property; Psychopathology; Quality of life; Reporting; Research; Research Personnel; Retrieval; Role; Self Concept; Sensory; Stimulus; Strategic Planning; Stress; Structure; Symptoms; Testing; Time; Trauma; Visual; Walkers; experience; improved; interest; memory retrieval; mental health related disorder; prospective; rehearsal; research study; vigilance

DESCRIPTION (provided by applicant): Autobiographical memory (AM) plays a central role in people's construction of a self-concept, their experience of personhood, and the way in which they interact with world around them. AM is fundamental to a host of important behaviors, such as learning (e.g., Pillemer, 2003), communication (Bluck & Alea, 2002), goal pursuit (e.g., Singer & Salovey, 1993), and imaging possible future events (e.g., Szpunar, 2010). When AM is lost because of amnesia (Burgess & Shallice, 1996) or Alzheimer's disease (Bayles, Kaszniak, & Tomoeda, 1991) the consequences are profound. Similarly, quality of life can be severely reduced when AMs are intensely negative - many forms of psychopathology involve stress-provoking and intrusive memories, such as post-traumatic stress disorder (PTSD; e.g., Rubin, Berntsen, & Bohni, 2008). Since the origins of systematic empirical research on AM (Freud, 1915; Galton, 1883), the field has generated much knowledge about nature and function of AM as it develops across the lifespan (for review see Conway et al., 2010). A basic question that has been thoroughly investigated is how the content (e.g., specific details of events, narrative structure, etc.) and phenomenological characteristics (e.g., emotional intensity, vividness, etc.) of AMs change over time. In order to explain why AMs change over time, researchers often invoke repeated retrieval of previously experienced events (i.e. "rehearsal") as a causal mechanism. However, the evidence for this claim is mostly correlational because AM studies usually measure retrieval retrospectively through subjective reports rather than manipulating it in prospective experiments. The broad goal of the proposed research is to test theoretical claims about how repeated retrieval affects AM and examine whether these effects differ in individuals with and without PTSD. More specifically, the proposed research will investigate how retrieval affects the content and phenomenological characteristics of AMs by performing prospective experiments in which the retrieval of AMs is manipulated as an independent variable. Critically, the theoretical claims that will be tested have direct implications for mental health. For example, one symptom of PTSD is the repeated retrieval of intensely negative, stress-provoking AMs - knowledge of how retrieval affects AM may enable the improvement of therapies involving the retrieval of memories to reduce the emotional intensity of trauma memories. The proposed research will advance Objectives #1 and #3 put forth in the NIMH Strategic Plan. The study will further our understanding of the behavioral and experiential factors that contribute to PTSD (Strategic Objective #1). In addition, the study will improve the efficacy of existing therapies tht are used for the treatment of PTSD, while also informing the treatment of other memory-related mental health disorders (Strategic Objective #3). PUBLIC HEALTH RELEVANCE: The proposed research will advance our understanding of how repeatedly retrieving positive and negative autobiographical memories affects the content (e.g., specific details of events, narrative structure, etc.) and phenomenological characteristics (e.g., emotional intensity, vividness, etc.) of these memories in people with and without post-traumatic stress disorder (PTSD). The findings will inform the treatment of PTSD as well as other memory-related mental health disorders, such as depression, phobias, and obsessive-compulsive disorder. For example, understanding how retrieval affects AMs in individuals with PTSD may enable the improvement of therapies aimed at reducing the emotional intensity and vividness of trauma memories.

描述（由申请人提供）：自传体记忆（AM）在人们构建自我概念、人格体验以及与周围世界互动的方式中起着核心作用。AM是许多重要行为的基础，例如学习（例如，Pillemer，2003年），沟通（Bluck & Alea，2002年），目标追求（例如，Singer & Salovey，1993），以及想象未来可能发生的事件（例如，Szpunar，2010）。当AM因健忘症（Burgess & Shallice，1996）或阿尔茨海默病（Bayles，Kaszniak，& Tomoeda，1991）而丢失时，后果是深远的。类似地，当AM强烈消极时，生活质量会严重降低-许多形式的精神病理学涉及引起压力和侵入性记忆，例如创伤后应激障碍（PTSD;例如，Rubin，Berntsen，& Bohni，2008）. 自从对AM的系统性实证研究的起源（Freud，1915; Galton，1883）以来，该领域已经产生了关于AM的性质和功能的许多知识，因为它在整个生命周期中发展（关于综述，参见Conway et al.，2010年）。已经彻底调查的一个基本问题是内容（例如，事件的具体细节、叙事结构等）和现象学特征（例如，情感的强烈、生动等）AM的变化随着时间的推移。为了解释为什么AM会随着时间的推移而变化，研究人员经常引用重复检索先前经历的事件（即“排练”）作为因果机制。然而，这一说法的证据大多是相关的，因为AM研究通常通过主观报告回顾性地测量检索，而不是操纵它。 前瞻性实验 拟议研究的广泛目标是测试关于重复提取如何影响AM的理论主张，并检查这些影响是否在有和没有PTSD的个体中存在差异。更具体地说，拟议的研究将调查如何检索影响的内容和现象学特征的AM进行前瞻性实验中，检索AM被操纵为一个独立的变量。至关重要的是，将被测试的理论主张对心理健康有直接影响。比如说， 创伤后应激障碍的一个症状是反复提取强烈的负面的、引起压力的AM--了解提取如何影响AM可以改进包括提取记忆以降低创伤记忆的情感强度的治疗。 拟议的研究将推进NIMH战略计划中提出的目标1和3。这项研究将进一步加深我们对导致PTSD的行为和经验因素的理解（战略目标#1）。此外，该研究将提高用于治疗PTSD的现有疗法的疗效，同时也为其他记忆相关心理健康障碍的治疗提供信息（战略目标#3）。 公共卫生相关性：这项拟议中的研究将促进我们对重复检索积极和消极自传体记忆如何影响内容的理解（例如，事件的具体细节、叙事结构等）和现象学特征（例如，情感的强烈、生动等）这些记忆在有和没有创伤后应激障碍（PTSD）的人身上的表现。这些发现将为创伤后应激障碍以及其他与记忆有关的心理健康障碍，如抑郁症，恐惧症和强迫症的治疗提供信息。例如，了解提取如何影响PTSD患者的AM可能有助于改善旨在降低创伤记忆的情绪强度和生动性的治疗方法。