Social Cognition Psychometric Evaluation

社会认知心理测量评估

• 批准号: 8246538
• 负责人: Philip D. Harvey
• 金额: $ 59.22万
• 依托单位: UNIVERSITY OF MIAMI SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-03-01 至 2017-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8246538
• 关键词: Address; Brain Diseases; Characteristics; Clinical assessments; Cognitive; Cognitive deficits; Complex; Consensus; Cues; Data; Development; Effectiveness; Elements; Emotions; Ensure; Evaluation; Factor Analysis; Goals; Impaired cognition; Impairment; Individual; Intervention; Intervention Studies; Joints; Link; Literature; Measurement; Measures; Mediating; Mental Health; Methodist Church; Mind; Modality; Modification; National Institute of Mental Health; Neurocognition; North Carolina; Outcome; Outcome Measure; Patients; Perception; Phase; Procedures; Process; Property; Psychometrics; Publishing; Research; Research Personnel; Role; Sampling; Schizophrenia; Site; Stimulus; Strategic Planning; Structure; Surveys; Testing; Treatment outcome; Universities; Validation; Validity and Reliability; base; cognitive neuroscience; experience; functional outcomes; improved; indexing; instrument; instrumentation; meetings; member; programs; psychosocial; rapid growth; response; social; social cognition; social skills; sound; standard measure; standardize measure; success; theories; validation studies

DESCRIPTION (provided by applicant): The present application is in response to Strategy 3.2 of the NIMH strategic plan, which requests the development of standardized measures of functional outcome that can be utilized in clinical assessment and intervention studies. This goal will be met by achieving a consensus definition of crucial social cognitive domains and developing psychometrically sound measures that can be used to assess these domains in various types of treatment research involving people with schizophrenia. Social cognition is a set of cognitive processes that are involved in how individuals understand and respond to social information. The social cognitive abilities of individuals with schizophrenia have been strongly linked to functional, real-world social outcomes, and social cognition is increasingly seen as a viable treatment target. It is therefore imperative that sensitive and psychometrically sound measures be developed for accurate assessment. The first phase of the proposed project will conduct an extensive survey of experts in the field to identify the core domains of social cognition and current tasks that assess each domain (Specific Aim 1). A carefully selected smaller group of expert panelists will then convene to evaluate each identified domain and task using consensus attainment procedures previously developed by the RAND Corporation and used in previous large-scale mental health assessment studies. The panel will reach a consensus on the most relevant domains of social cognition and select the most promising tasks within each domain for further study and development (Specific Aim 2). These candidate measures will then be compiled into a comprehensive battery and administered to a large sample of individuals with schizophrenia and healthy controls at two different sites (University of Miami and Southern Methodist University). Data will be utilized to assess the reliability and validity characteristics of each task (Specific Aim 3). Data from this psychometric study will be shared with a scientific advisory group to evaluate the results. Otherwise promising candidate measures that show inadequate characteristics will then be modified and pilot tested to ensure the success of the modifications (Specific Aim 4). Finally, a three-site validation study (to increase the generalizability of the findings) will then be conducted to determine the psychometric properties of the final measures (Specific Aim 5). Data from this portion of the project will also be used to systematically examine the relationship between these refined social cognition measures and aspects of functional outcome. The findings of this project will yield a uniform definition of social cognition that will guide future research and develop psychometrically sound measures of social cognition that will be valuable in assessing the effectiveness of psychosocial and biomedical interventions. PUBLIC HEALTH RELEVANCE: Schizophrenia is a complex brain disorder that includes significant impairments in the ability to function in everyday settings that are clearly related to social cognitive deficits. Empirically based and sound instrumentation is key to assessing the outcomes of interventions targeted to ameliorate social cognitive impairments. The goal of the proposed study is to identify and improve the best existing measures of social cognition so that they can be suitably applied in large-scale treatment studies. This project will develop consensus on the critical elements of social cognition, identify the best existing measures of social cognition, collect new data to evaluate the psychometric characteristics of these measures, modify them to optimize their utility, and collect additional data to determine the psychometric properties of the final measures based on a large and diverse sample, while focusing continuously on real-world functional outcomes and the role of social cognition, as compared to neurocognition and social competence, for the prediction of real-world functioning

描述（由申请人提供）：本申请是对NIMH战略计划的战略3.2的回应，该战略计划要求开发可用于临床评估和干预研究的功能结局的标准化测量。这一目标将通过实现关键社会认知领域的共识定义和发展心理测量学上的健全措施来实现，这些措施可用于评估涉及精神分裂症患者的各种类型的治疗研究中的这些领域。社会认知是一组涉及个体如何理解和响应社会信息的认知过程。精神分裂症患者的社会认知能力与功能性的、现实世界的社会结果密切相关，社会认知越来越被视为一个可行的治疗目标。因此，必须制定敏感和心理测量健全的措施，以进行准确的评估。拟议项目的第一阶段将对该领域的专家进行广泛调查，以确定社会认知的核心领域和评估每个领域的当前任务（具体目标1）。然后，一个精心挑选的专家小组成员小组将召开会议，使用兰德公司以前开发的并用于以前大规模心理健康评估研究的共识达成程序来评估每个确定的领域和任务。小组将就社会认知的最相关领域达成共识，并选择每个领域中最有前途的任务进行进一步研究和开发（具体目标2）。然后将这些候选指标汇编成一个综合性的成套测试，并在两个不同的地点（迈阿密大学和南卫理公会大学）对精神分裂症患者和健康对照者的大样本进行管理。数据将用于评估每个任务的可靠性和有效性特征（具体目标3）。这项心理测量学研究的数据将与一个科学咨询小组分享，以评估结果。否则，将对显示出不足特征的有希望的候选措施进行修改和试点测试，以确保修改的成功（具体目标4）。最后，将进行三个地点的验证研究（以增加调查结果的普遍性），以确定最终措施的心理测量特性（具体目标5）。从该项目的这一部分的数据也将被用来系统地检查这些完善的社会认知措施和功能结果方面之间的关系。该项目的研究结果将产生一个统一的社会认知的定义，这将指导未来的研究和发展社会认知的心理测量健全的措施，这将是有价值的评估心理社会和生物医学干预措施的有效性。 公共卫生相关性：精神分裂症是一种复杂的大脑疾病，包括在日常环境中发挥作用的能力明显受损，这显然与社会认知缺陷有关。以经验为基础和健全的仪器是评估干预措施的结果，以改善社会认知障碍的关键。这项研究的目的是确定和改进现有的最佳社会认知措施，使其能够适用于大规模的治疗研究。该项目将就社会认知的关键要素达成共识，确定现有的最佳社会认知措施，收集新数据以评估这些措施的心理测量特征，修改它们以优化其效用，并收集额外数据以确定基于大规模和多样化样本的最终措施的心理测量特性，同时不断关注现实世界的功能结果和社会认知（与神经认知和社会能力相比）在预测现实世界功能方面的作用